Local Drug Delivery of Alendronate Gel for the Treatment of Patients With Chronic Periodontitis With Diabetes Mellitus: A Double‐Masked Controlled Clinical Trial

Background: Alendronate (ALN) increases alveolar bone density with systemic use and, has been found to increase bone formation on local delivery into the periodontal pocket. The purpose of the present study is to explore the efficacy of 1% ALN gel as a local drug delivery system in adjunct to scalin...

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Veröffentlicht in:	Journal of periodontology (1970) 2012-10, Vol.83 (10), p.1322-1328
Hauptverfasser:	Pradeep, A. R., Sharma, Anuj, Rao, Nishanth S., Bajaj, Pavan, Naik, Savitha B., Kumari, Minal
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alendronate Alendronate - administration & dosage Alveolar Bone Loss - diagnostic imaging Alveolar Bone Loss - drug therapy Alveolar Bone Loss - therapy Biological and medical sciences Bone Density Conservation Agents - administration & dosage Bone Regeneration Bones, joints and connective tissue. Antiinflammatory agents Chi-Square Distribution chronic periodontitis Chronic Periodontitis - complications Chronic Periodontitis - drug therapy Chronic Periodontitis - therapy Confidence Intervals Dental Plaque Index Dentistry diabetes mellitus Diabetes Mellitus, Type 2 - complications Diabetes. Impaired glucose tolerance Double-Blind Method Drug Delivery Systems Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Facial bones, jaws, teeth, parodontium: diseases, semeiology Female Gels - chemistry Humans Injections, Intralesional Male Medical sciences Middle Aged Non tumoral diseases Otorhinolaryngology. Stomatology Periodontal Index Periodontal Pocket - drug therapy Pharmacology. Drug treatments Prospective Studies Radiography regeneration Young Adult
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