Vascular placental abnormalities and newborn death in a pregnant diabetic woman with familial partial lipodystrophy type 3: A possible role for peroxisome proliferator-activated receptor γ

Abstract The peroxisome proliferator-activated receptor protein gamma (PPARγ), a nuclear receptor involved in adipocyte differentiation, energy homoeostasis and fat storage, can lead, in rare cases of coding mutations, to familial partial lipodystrophy type 3 (FPLD3) with severe insulin resistance....

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