Nasal deposition and clearance in man: comparison of a bidirectional powder device and a traditional liquid spray pump

Delivery of powder formulations to the nose is an attractive alternative for many drugs and vaccines. This study compared the regional nasal deposition and clearance patterns of lactose powder delivered by the OptiNose powder device (Opt-Powder; OptiNose US Inc., Yardley, PA, USA) to that of liquid...

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Veröffentlicht in:	Journal of aerosol medicine 2012-10, Vol.25 (5), p.280-289
Hauptverfasser:	Djupesland, Per Gisle, Skretting, Arne
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intranasal Adult Aerosols Cross-Over Studies Drug Delivery Systems Equipment Design Female Health technology assessment Humans Lactose - administration & dosage Lung - metabolism Magnetic Resonance Imaging Male Nasal Cavity - metabolism Nasal Mucosa - metabolism Powders Technetium - chemistry Technetium Tc 99m Pentetate - administration & dosage Young Adult
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