Vasospastic angina in a patient with hyperthyroidism
A 56-year-old man presented with typical angina pectoris lasting >20 min associated with precordial ST-segment elevation. Urgent coronary angiography showed critical stenosis in the proximal segment of the left anterior descending artery, which resolved with intracoronary nitrate application. He...
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| Veröffentlicht in: | Herz 2012-08, Vol.37 (5), p.570-572 |
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| creator | Canpolat, U. Sunman, H. Gürses, K.M. Aytemir, K. |
| description | A 56-year-old man presented with typical angina pectoris lasting >20 min associated with precordial ST-segment elevation. Urgent coronary angiography showed critical stenosis in the proximal segment of the left anterior descending artery, which resolved with intracoronary nitrate application. He was subsequently diagnosed with hyperthyroidism secondary to exposure of iodinated contrast agent which is thought to be the cause of the coronary spasm. Symptoms resolved upon treatment with propylthiouracil, slow-release diltiazem, isosorbide mononitrate, and aspirin. This unusual case highlights the importance of considering hyperthyroidism in the differential diagnosis of chest pain and coronary artery spasm. We suggest routine thyroid function testing in patients with coronary spasm. |
| doi_str_mv | 10.1007/s00059-011-3572-y |
| format | Article |
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Urgent coronary angiography showed critical stenosis in the proximal segment of the left anterior descending artery, which resolved with intracoronary nitrate application. He was subsequently diagnosed with hyperthyroidism secondary to exposure of iodinated contrast agent which is thought to be the cause of the coronary spasm. Symptoms resolved upon treatment with propylthiouracil, slow-release diltiazem, isosorbide mononitrate, and aspirin. This unusual case highlights the importance of considering hyperthyroidism in the differential diagnosis of chest pain and coronary artery spasm. 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Urgent coronary angiography showed critical stenosis in the proximal segment of the left anterior descending artery, which resolved with intracoronary nitrate application. He was subsequently diagnosed with hyperthyroidism secondary to exposure of iodinated contrast agent which is thought to be the cause of the coronary spasm. Symptoms resolved upon treatment with propylthiouracil, slow-release diltiazem, isosorbide mononitrate, and aspirin. This unusual case highlights the importance of considering hyperthyroidism in the differential diagnosis of chest pain and coronary artery spasm. We suggest routine thyroid function testing in patients with coronary spasm.</description><subject>Angina Pectoris - diagnosis</subject><subject>Angina Pectoris - etiology</subject><subject>Cardiology</subject><subject>Case Study</subject><subject>Coronary Vasospasm - diagnosis</subject><subject>Coronary Vasospasm - etiology</subject><subject>Diagnosis, Differential</subject><subject>Humans</subject><subject>Hyperthyroidism - complications</subject><subject>Hyperthyroidism - diagnosis</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><issn>0340-9937</issn><issn>1615-6692</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kMtKxDAUhoMozjj6AG6k4MZN9SRtbksZvIHgRt2GNE1nMkwvJi3StzdDRxHB1Vmc7__P4UPoHMM1BuA3AQCoTAHjNKOcpOMBmmOGacqYJIdoDlkOqZQZn6GTEDYAmEoCx2hGSA48J2SO8ncd2tDp0DuT6GblGp24JtFJp3tnmz75dP06WY-d9f169K0rXahP0VGlt8Ge7ecCvd3fvS4f0-eXh6fl7XNqMk76tBCYao0LKqiVzBBhTAaZoawgkguRS820FSJ-SXODaV5JYzjmROC8sqUsswW6mno7334MNvSqdsHY7VY3th2CwiAg9giKI3r5B920g2_id5EiUkjGGEQKT5TxbQjeVqrzrtZ-jJDaKVWTUhWVqp1SNcbMxb55KGpb_iS-HUaATECIq2Zl_e_T_7V-AcO4f88</recordid><startdate>20120801</startdate><enddate>20120801</enddate><creator>Canpolat, U.</creator><creator>Sunman, H.</creator><creator>Gürses, K.M.</creator><creator>Aytemir, K.</creator><general>Urban and Vogel</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TS</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20120801</creationdate><title>Vasospastic angina in a patient with hyperthyroidism</title><author>Canpolat, U. ; 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| subjects | Angina Pectoris - diagnosis Angina Pectoris - etiology Cardiology Case Study Coronary Vasospasm - diagnosis Coronary Vasospasm - etiology Diagnosis, Differential Humans Hyperthyroidism - complications Hyperthyroidism - diagnosis Internal Medicine Male Medicine Medicine & Public Health Middle Aged |
| title | Vasospastic angina in a patient with hyperthyroidism |
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