Demographic and Geographic Vascular Risk Factor Differences in European Young Adults With Ischemic Stroke: The 15 Cities Young Stroke Study
We compared among young patients with ischemic stroke the distribution of vascular risk factors among sex, age groups, and 3 distinct geographic regions in Europe. We included patients with first-ever ischemic stroke aged 15 to 49 years from existing hospital- or population-based prospective or cons...
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| Veröffentlicht in: | Stroke (1970) 2012-10, Vol.43 (10), p.2624-2630 |
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| creator | Putaala, Jukka Yesilot, Nilufer Waje-Andreassen, Ulrike Pitkäniemi, Janne Vassilopoulou, Sofia Nardi, Katiuscia Odier, Celine Hofgart, Gergely Engelter, Stefan Burow, Annika Mihalka, Laszlo Kloss, Manja Ferrari, Julia Lemmens, Robin Coban, Oguzhan Haapaniemi, Elena Maaijwee, Noortje Rutten-Jacobs, Loes Bersano, Anna Cereda, Carlo Baron, Pierluigi Borellini, Linda Valcarenghi, Caterina Thomassen, Lars Grau, Armin J. Palm, Frederick Urbanek, Christian Tuncay, Rezzan Durukan-Tolvanen, Aysan van Dijk, Ewoud J. de Leeuw, Frank-Erik Thijs, Vincent Greisenegger, Stefan Vemmos, Konstantinos Lichy, Christoph Bereczki, Daniel Csiba, Laszlo Michel, Patrik Leys, Didier Spengos, Konstantinos Naess, Halvor Bahar, Sara Zarko Tatlisumak, Turgut |
| description | We compared among young patients with ischemic stroke the distribution of vascular risk factors among sex, age groups, and 3 distinct geographic regions in Europe.
We included patients with first-ever ischemic stroke aged 15 to 49 years from existing hospital- or population-based prospective or consecutive young stroke registries involving 15 cities in 12 countries. Geographic regions were defined as northern (Finland, Norway), central (Austria, Belgium, France, Germany, Hungary, The Netherlands, Switzerland), and southern (Greece, Italy, Turkey) Europe. Hierarchical regression models were used for comparisons.
In the study cohort (n=3944), the 3 most frequent risk factors were current smoking (48.7%), dyslipidemia (45.8%), and hypertension (35.9%). Compared with central (n=1868; median age, 43 years) and northern (n=1330; median age, 44 years) European patients, southern Europeans (n=746; median age, 41 years) were younger. No sex difference emerged between the regions, male:female ratio being 0.7 in those aged |
| doi_str_mv | 10.1161/STROKEAHA.112.662866 |
| format | Article |
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We included patients with first-ever ischemic stroke aged 15 to 49 years from existing hospital- or population-based prospective or consecutive young stroke registries involving 15 cities in 12 countries. Geographic regions were defined as northern (Finland, Norway), central (Austria, Belgium, France, Germany, Hungary, The Netherlands, Switzerland), and southern (Greece, Italy, Turkey) Europe. Hierarchical regression models were used for comparisons.
In the study cohort (n=3944), the 3 most frequent risk factors were current smoking (48.7%), dyslipidemia (45.8%), and hypertension (35.9%). Compared with central (n=1868; median age, 43 years) and northern (n=1330; median age, 44 years) European patients, southern Europeans (n=746; median age, 41 years) were younger. No sex difference emerged between the regions, male:female ratio being 0.7 in those aged <34 years and reaching 1.7 in those aged 45 to 49 years. After accounting for confounders, no risk-factor differences emerged at the region level. Compared with females, males were older and they more frequently had dyslipidemia or coronary heart disease, or were smokers, irrespective of region. In both sexes, prevalence of family history of stroke, dyslipidemia, smoking, hypertension, diabetes mellitus, coronary heart disease, peripheral arterial disease, and atrial fibrillation positively correlated with age across all regions.
Primary preventive strategies for ischemic stroke in young adults-having high rate of modifiable risk factors-should be targeted according to sex and age at continental level.</description><identifier>ISSN: 0039-2499</identifier><identifier>EISSN: 1524-4628</identifier><identifier>DOI: 10.1161/STROKEAHA.112.662866</identifier><identifier>PMID: 22798330</identifier><identifier>CODEN: SJCCA7</identifier><language>eng</language><publisher>Hagerstown, MD: American Heart Association, Inc</publisher><subject>Adolescent ; Adult ; Age Factors ; Biological and medical sciences ; Cohort Studies ; Demography ; Dyslipidemias - complications ; Europe - epidemiology ; Female ; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy ; Humans ; Hypertension - complications ; Male ; Medical sciences ; Middle Aged ; Nervous system (semeiology, syndromes) ; Neurology ; Prospective Studies ; Registries ; Regression Analysis ; Risk Factors ; Sex Factors ; Smoking - adverse effects ; Stroke - epidemiology ; Stroke - ethnology ; Time Factors ; Vascular diseases and vascular malformations of the nervous system ; Young Adult</subject><ispartof>Stroke (1970), 2012-10, Vol.43 (10), p.2624-2630</ispartof><rights>American Heart Association, Inc.</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3316-2db34c72b0beb4a714d85c41cca10c48f22273a501ca3f877d1e57317b14b6863</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,3674,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26403143$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22798330$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Putaala, Jukka</creatorcontrib><creatorcontrib>Yesilot, Nilufer</creatorcontrib><creatorcontrib>Waje-Andreassen, Ulrike</creatorcontrib><creatorcontrib>Pitkäniemi, Janne</creatorcontrib><creatorcontrib>Vassilopoulou, Sofia</creatorcontrib><creatorcontrib>Nardi, Katiuscia</creatorcontrib><creatorcontrib>Odier, Celine</creatorcontrib><creatorcontrib>Hofgart, Gergely</creatorcontrib><creatorcontrib>Engelter, Stefan</creatorcontrib><creatorcontrib>Burow, Annika</creatorcontrib><creatorcontrib>Mihalka, Laszlo</creatorcontrib><creatorcontrib>Kloss, Manja</creatorcontrib><creatorcontrib>Ferrari, Julia</creatorcontrib><creatorcontrib>Lemmens, Robin</creatorcontrib><creatorcontrib>Coban, Oguzhan</creatorcontrib><creatorcontrib>Haapaniemi, Elena</creatorcontrib><creatorcontrib>Maaijwee, Noortje</creatorcontrib><creatorcontrib>Rutten-Jacobs, Loes</creatorcontrib><creatorcontrib>Bersano, Anna</creatorcontrib><creatorcontrib>Cereda, Carlo</creatorcontrib><creatorcontrib>Baron, Pierluigi</creatorcontrib><creatorcontrib>Borellini, Linda</creatorcontrib><creatorcontrib>Valcarenghi, Caterina</creatorcontrib><creatorcontrib>Thomassen, Lars</creatorcontrib><creatorcontrib>Grau, Armin J.</creatorcontrib><creatorcontrib>Palm, Frederick</creatorcontrib><creatorcontrib>Urbanek, Christian</creatorcontrib><creatorcontrib>Tuncay, Rezzan</creatorcontrib><creatorcontrib>Durukan-Tolvanen, Aysan</creatorcontrib><creatorcontrib>van Dijk, Ewoud J.</creatorcontrib><creatorcontrib>de Leeuw, Frank-Erik</creatorcontrib><creatorcontrib>Thijs, Vincent</creatorcontrib><creatorcontrib>Greisenegger, Stefan</creatorcontrib><creatorcontrib>Vemmos, Konstantinos</creatorcontrib><creatorcontrib>Lichy, Christoph</creatorcontrib><creatorcontrib>Bereczki, Daniel</creatorcontrib><creatorcontrib>Csiba, Laszlo</creatorcontrib><creatorcontrib>Michel, Patrik</creatorcontrib><creatorcontrib>Leys, Didier</creatorcontrib><creatorcontrib>Spengos, Konstantinos</creatorcontrib><creatorcontrib>Naess, Halvor</creatorcontrib><creatorcontrib>Bahar, Sara Zarko</creatorcontrib><creatorcontrib>Tatlisumak, Turgut</creatorcontrib><title>Demographic and Geographic Vascular Risk Factor Differences in European Young Adults With Ischemic Stroke: The 15 Cities Young Stroke Study</title><title>Stroke (1970)</title><addtitle>Stroke</addtitle><description>We compared among young patients with ischemic stroke the distribution of vascular risk factors among sex, age groups, and 3 distinct geographic regions in Europe.
We included patients with first-ever ischemic stroke aged 15 to 49 years from existing hospital- or population-based prospective or consecutive young stroke registries involving 15 cities in 12 countries. Geographic regions were defined as northern (Finland, Norway), central (Austria, Belgium, France, Germany, Hungary, The Netherlands, Switzerland), and southern (Greece, Italy, Turkey) Europe. Hierarchical regression models were used for comparisons.
In the study cohort (n=3944), the 3 most frequent risk factors were current smoking (48.7%), dyslipidemia (45.8%), and hypertension (35.9%). Compared with central (n=1868; median age, 43 years) and northern (n=1330; median age, 44 years) European patients, southern Europeans (n=746; median age, 41 years) were younger. No sex difference emerged between the regions, male:female ratio being 0.7 in those aged <34 years and reaching 1.7 in those aged 45 to 49 years. After accounting for confounders, no risk-factor differences emerged at the region level. Compared with females, males were older and they more frequently had dyslipidemia or coronary heart disease, or were smokers, irrespective of region. In both sexes, prevalence of family history of stroke, dyslipidemia, smoking, hypertension, diabetes mellitus, coronary heart disease, peripheral arterial disease, and atrial fibrillation positively correlated with age across all regions.
Primary preventive strategies for ischemic stroke in young adults-having high rate of modifiable risk factors-should be targeted according to sex and age at continental level.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Biological and medical sciences</subject><subject>Cohort Studies</subject><subject>Demography</subject><subject>Dyslipidemias - complications</subject><subject>Europe - epidemiology</subject><subject>Female</subject><subject>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy</subject><subject>Humans</subject><subject>Hypertension - complications</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Prospective Studies</subject><subject>Registries</subject><subject>Regression Analysis</subject><subject>Risk Factors</subject><subject>Sex Factors</subject><subject>Smoking - adverse effects</subject><subject>Stroke - epidemiology</subject><subject>Stroke - ethnology</subject><subject>Time Factors</subject><subject>Vascular diseases and vascular malformations of the nervous system</subject><subject>Young Adult</subject><issn>0039-2499</issn><issn>1524-4628</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkd1q3DAQhUVpabZJ36AU3RR641QjybK3d8tm80MDgWST0Csjy-NYXf9sJIuQZ8hLR8HbzYUYDvrODDOHkG_AjgEU_LpZX1_9WS3OF1HyY6V4rtQHMoOUy0RG9ZHMGBPzhMv5_IB88f4fY4yLPP1MDjjP5rkQbEZeTrAbHpzeNtZQ3Vf0DPfyTnsTWu3otfUbeqrNODh6YusaHfYGPbU9XQU3bFH39O8Q-ge6qEI7enpvx4ZeeNNgF_vcjG7Y4G-6bpBCSpd2tNE8Gaa_WEL1fEQ-1br1-HVXD8nt6Wq9PE8ur84ulovLxAgBKuFVKaTJeMlKLKXOQFZ5aiQYo4EZmdc8rid0ysBoUedZVgGmmYCsBFmqXIlD8nPqu3XDY0A_Fp31BttW9zgEXwDLmZIslzyickKNG7x3WBdbZzvtniNUvMVQ7GOIkhdTDNH2fTchlB1We9P_u0fgxw6IN9Zt7XRvrH_n4ngBUrzPfxraEZ3ftOEJXdGgbsemiIGyTGUs4Qw4vKkkPlDiFSszoHM</recordid><startdate>20121001</startdate><enddate>20121001</enddate><creator>Putaala, Jukka</creator><creator>Yesilot, Nilufer</creator><creator>Waje-Andreassen, Ulrike</creator><creator>Pitkäniemi, Janne</creator><creator>Vassilopoulou, Sofia</creator><creator>Nardi, Katiuscia</creator><creator>Odier, Celine</creator><creator>Hofgart, Gergely</creator><creator>Engelter, Stefan</creator><creator>Burow, Annika</creator><creator>Mihalka, Laszlo</creator><creator>Kloss, Manja</creator><creator>Ferrari, Julia</creator><creator>Lemmens, Robin</creator><creator>Coban, Oguzhan</creator><creator>Haapaniemi, Elena</creator><creator>Maaijwee, Noortje</creator><creator>Rutten-Jacobs, Loes</creator><creator>Bersano, Anna</creator><creator>Cereda, Carlo</creator><creator>Baron, Pierluigi</creator><creator>Borellini, Linda</creator><creator>Valcarenghi, Caterina</creator><creator>Thomassen, Lars</creator><creator>Grau, Armin J.</creator><creator>Palm, Frederick</creator><creator>Urbanek, Christian</creator><creator>Tuncay, Rezzan</creator><creator>Durukan-Tolvanen, Aysan</creator><creator>van Dijk, Ewoud J.</creator><creator>de Leeuw, Frank-Erik</creator><creator>Thijs, Vincent</creator><creator>Greisenegger, Stefan</creator><creator>Vemmos, Konstantinos</creator><creator>Lichy, Christoph</creator><creator>Bereczki, Daniel</creator><creator>Csiba, Laszlo</creator><creator>Michel, Patrik</creator><creator>Leys, Didier</creator><creator>Spengos, Konstantinos</creator><creator>Naess, Halvor</creator><creator>Bahar, Sara Zarko</creator><creator>Tatlisumak, Turgut</creator><general>American Heart Association, Inc</general><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20121001</creationdate><title>Demographic and Geographic Vascular Risk Factor Differences in European Young Adults With Ischemic Stroke: The 15 Cities Young Stroke Study</title><author>Putaala, Jukka ; Yesilot, Nilufer ; Waje-Andreassen, Ulrike ; Pitkäniemi, Janne ; Vassilopoulou, Sofia ; Nardi, Katiuscia ; Odier, Celine ; Hofgart, Gergely ; Engelter, Stefan ; Burow, Annika ; Mihalka, Laszlo ; Kloss, Manja ; Ferrari, Julia ; Lemmens, Robin ; Coban, Oguzhan ; Haapaniemi, Elena ; Maaijwee, Noortje ; Rutten-Jacobs, Loes ; Bersano, Anna ; Cereda, Carlo ; Baron, Pierluigi ; Borellini, Linda ; Valcarenghi, Caterina ; Thomassen, Lars ; Grau, Armin J. ; Palm, Frederick ; Urbanek, Christian ; Tuncay, Rezzan ; Durukan-Tolvanen, Aysan ; van Dijk, Ewoud J. ; de Leeuw, Frank-Erik ; Thijs, Vincent ; Greisenegger, Stefan ; Vemmos, Konstantinos ; Lichy, Christoph ; Bereczki, Daniel ; Csiba, Laszlo ; Michel, Patrik ; Leys, Didier ; Spengos, Konstantinos ; Naess, Halvor ; Bahar, Sara Zarko ; Tatlisumak, Turgut</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3316-2db34c72b0beb4a714d85c41cca10c48f22273a501ca3f877d1e57317b14b6863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Biological and medical sciences</topic><topic>Cohort Studies</topic><topic>Demography</topic><topic>Dyslipidemias - complications</topic><topic>Europe - epidemiology</topic><topic>Female</topic><topic>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy</topic><topic>Humans</topic><topic>Hypertension - complications</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Prospective Studies</topic><topic>Registries</topic><topic>Regression Analysis</topic><topic>Risk Factors</topic><topic>Sex Factors</topic><topic>Smoking - adverse effects</topic><topic>Stroke - epidemiology</topic><topic>Stroke - ethnology</topic><topic>Time Factors</topic><topic>Vascular diseases and vascular malformations of the nervous system</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Putaala, Jukka</creatorcontrib><creatorcontrib>Yesilot, Nilufer</creatorcontrib><creatorcontrib>Waje-Andreassen, Ulrike</creatorcontrib><creatorcontrib>Pitkäniemi, Janne</creatorcontrib><creatorcontrib>Vassilopoulou, Sofia</creatorcontrib><creatorcontrib>Nardi, Katiuscia</creatorcontrib><creatorcontrib>Odier, Celine</creatorcontrib><creatorcontrib>Hofgart, Gergely</creatorcontrib><creatorcontrib>Engelter, Stefan</creatorcontrib><creatorcontrib>Burow, Annika</creatorcontrib><creatorcontrib>Mihalka, Laszlo</creatorcontrib><creatorcontrib>Kloss, Manja</creatorcontrib><creatorcontrib>Ferrari, Julia</creatorcontrib><creatorcontrib>Lemmens, Robin</creatorcontrib><creatorcontrib>Coban, Oguzhan</creatorcontrib><creatorcontrib>Haapaniemi, Elena</creatorcontrib><creatorcontrib>Maaijwee, Noortje</creatorcontrib><creatorcontrib>Rutten-Jacobs, Loes</creatorcontrib><creatorcontrib>Bersano, Anna</creatorcontrib><creatorcontrib>Cereda, Carlo</creatorcontrib><creatorcontrib>Baron, Pierluigi</creatorcontrib><creatorcontrib>Borellini, Linda</creatorcontrib><creatorcontrib>Valcarenghi, Caterina</creatorcontrib><creatorcontrib>Thomassen, Lars</creatorcontrib><creatorcontrib>Grau, Armin J.</creatorcontrib><creatorcontrib>Palm, Frederick</creatorcontrib><creatorcontrib>Urbanek, Christian</creatorcontrib><creatorcontrib>Tuncay, Rezzan</creatorcontrib><creatorcontrib>Durukan-Tolvanen, Aysan</creatorcontrib><creatorcontrib>van Dijk, Ewoud J.</creatorcontrib><creatorcontrib>de Leeuw, Frank-Erik</creatorcontrib><creatorcontrib>Thijs, Vincent</creatorcontrib><creatorcontrib>Greisenegger, Stefan</creatorcontrib><creatorcontrib>Vemmos, Konstantinos</creatorcontrib><creatorcontrib>Lichy, Christoph</creatorcontrib><creatorcontrib>Bereczki, Daniel</creatorcontrib><creatorcontrib>Csiba, Laszlo</creatorcontrib><creatorcontrib>Michel, Patrik</creatorcontrib><creatorcontrib>Leys, Didier</creatorcontrib><creatorcontrib>Spengos, Konstantinos</creatorcontrib><creatorcontrib>Naess, Halvor</creatorcontrib><creatorcontrib>Bahar, Sara Zarko</creatorcontrib><creatorcontrib>Tatlisumak, Turgut</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Stroke (1970)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Putaala, Jukka</au><au>Yesilot, Nilufer</au><au>Waje-Andreassen, Ulrike</au><au>Pitkäniemi, Janne</au><au>Vassilopoulou, Sofia</au><au>Nardi, Katiuscia</au><au>Odier, Celine</au><au>Hofgart, Gergely</au><au>Engelter, Stefan</au><au>Burow, Annika</au><au>Mihalka, Laszlo</au><au>Kloss, Manja</au><au>Ferrari, Julia</au><au>Lemmens, Robin</au><au>Coban, Oguzhan</au><au>Haapaniemi, Elena</au><au>Maaijwee, Noortje</au><au>Rutten-Jacobs, Loes</au><au>Bersano, Anna</au><au>Cereda, Carlo</au><au>Baron, Pierluigi</au><au>Borellini, Linda</au><au>Valcarenghi, Caterina</au><au>Thomassen, Lars</au><au>Grau, Armin J.</au><au>Palm, Frederick</au><au>Urbanek, Christian</au><au>Tuncay, Rezzan</au><au>Durukan-Tolvanen, Aysan</au><au>van Dijk, Ewoud J.</au><au>de Leeuw, Frank-Erik</au><au>Thijs, Vincent</au><au>Greisenegger, Stefan</au><au>Vemmos, Konstantinos</au><au>Lichy, Christoph</au><au>Bereczki, Daniel</au><au>Csiba, Laszlo</au><au>Michel, Patrik</au><au>Leys, Didier</au><au>Spengos, Konstantinos</au><au>Naess, Halvor</au><au>Bahar, Sara Zarko</au><au>Tatlisumak, Turgut</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Demographic and Geographic Vascular Risk Factor Differences in European Young Adults With Ischemic Stroke: The 15 Cities Young Stroke Study</atitle><jtitle>Stroke (1970)</jtitle><addtitle>Stroke</addtitle><date>2012-10-01</date><risdate>2012</risdate><volume>43</volume><issue>10</issue><spage>2624</spage><epage>2630</epage><pages>2624-2630</pages><issn>0039-2499</issn><eissn>1524-4628</eissn><coden>SJCCA7</coden><abstract>We compared among young patients with ischemic stroke the distribution of vascular risk factors among sex, age groups, and 3 distinct geographic regions in Europe.
We included patients with first-ever ischemic stroke aged 15 to 49 years from existing hospital- or population-based prospective or consecutive young stroke registries involving 15 cities in 12 countries. Geographic regions were defined as northern (Finland, Norway), central (Austria, Belgium, France, Germany, Hungary, The Netherlands, Switzerland), and southern (Greece, Italy, Turkey) Europe. Hierarchical regression models were used for comparisons.
In the study cohort (n=3944), the 3 most frequent risk factors were current smoking (48.7%), dyslipidemia (45.8%), and hypertension (35.9%). Compared with central (n=1868; median age, 43 years) and northern (n=1330; median age, 44 years) European patients, southern Europeans (n=746; median age, 41 years) were younger. No sex difference emerged between the regions, male:female ratio being 0.7 in those aged <34 years and reaching 1.7 in those aged 45 to 49 years. After accounting for confounders, no risk-factor differences emerged at the region level. Compared with females, males were older and they more frequently had dyslipidemia or coronary heart disease, or were smokers, irrespective of region. In both sexes, prevalence of family history of stroke, dyslipidemia, smoking, hypertension, diabetes mellitus, coronary heart disease, peripheral arterial disease, and atrial fibrillation positively correlated with age across all regions.
Primary preventive strategies for ischemic stroke in young adults-having high rate of modifiable risk factors-should be targeted according to sex and age at continental level.</abstract><cop>Hagerstown, MD</cop><pub>American Heart Association, Inc</pub><pmid>22798330</pmid><doi>10.1161/STROKEAHA.112.662866</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0039-2499 |
| ispartof | Stroke (1970), 2012-10, Vol.43 (10), p.2624-2630 |
| issn | 0039-2499 1524-4628 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1080640842 |
| source | Journals@Ovid Ovid Autoload; MEDLINE; American Heart Association Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adolescent Adult Age Factors Biological and medical sciences Cohort Studies Demography Dyslipidemias - complications Europe - epidemiology Female Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Hypertension - complications Male Medical sciences Middle Aged Nervous system (semeiology, syndromes) Neurology Prospective Studies Registries Regression Analysis Risk Factors Sex Factors Smoking - adverse effects Stroke - epidemiology Stroke - ethnology Time Factors Vascular diseases and vascular malformations of the nervous system Young Adult |
| title | Demographic and Geographic Vascular Risk Factor Differences in European Young Adults With Ischemic Stroke: The 15 Cities Young Stroke Study |
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