Transition path from two apposed membranes to a stalk obtained by a combination of particle simulations and string method

The formation of an hourglass-shaped passage (stalk) connecting two apposed membranes is an essential initial step in membrane fusion. The most probable transition path from two separate membranes to a stalk, i.e., the minimum free-energy path (MFEP), is constructed using a combination of particle s...

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Veröffentlicht in:	Physical review letters 2012-05, Vol.108 (22), p.228103-228103, Article 228103
Hauptverfasser:	Müller, Marcus, Smirnova, Yuliya G, Marelli, Giovanni, Fuhrmans, Marc, Shi, An-Chang
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Membrane - metabolism Computer Simulation Membrane Fusion - physiology Models, Biological Thermodynamics
Online-Zugang:	Volltext
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