Epidermal growth factor receptor (EGFR) inhibitors and derived treatments

Epidermal growth factor receptor inhibitors are used to treat advanced lung cancer patients for almost a decade. Current knowledge on their role in the first or subsequent lines of therapy serves as a model for other targeted therapies in development. Several molecular predictors of outcomes were su...

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Veröffentlicht in:	Annals of oncology 2012-09, Vol.23 Suppl 10, p.x193-x196
Hauptverfasser:	Dziadziuszko, R, Jassem, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Afatinib Antibodies, Monoclonal - therapeutic use Antibodies, Monoclonal, Humanized Antineoplastic Agents - therapeutic use Biomarkers, Pharmacological Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - pathology Cetuximab ErbB Receptors - antagonists & inhibitors ErbB Receptors - genetics Erlotinib Hydrochloride Gefitinib Humans Lung Neoplasms - drug therapy Lung Neoplasms - genetics Lung Neoplasms - pathology Neoplasm Staging Prognosis Quinazolines - therapeutic use Quinolines - therapeutic use Translational Medical Research Treatment Outcome
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