IL1B and VWF Variants Are Associated With Fibrinolytic Early Recanalization in Patients With Ischemic Stroke

There is a great interindividual variability among patients with acute ischemic stroke regarding the response to intravenous tissue-type plasminogen activator treatment. The aim of this study was to identify genetic variants associated with recanalization, and thus treatment efficacy, after tissue-t...

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Veröffentlicht in:	Stroke (1970) 2012-10, Vol.43 (10), p.2659-2665
Hauptverfasser:	Fernández-Cadenas, Israel, del Río-Espínola, Alberto, Giralt, Dolors, Domingues-Montanari, Sophie, Quiroga, Adoracion, Mendióroz, Maite, Ruíz, Agustin, Ribó, Marc, Serena, Joaquin, Obach, Victor, Freijo, Mari Mar, Martí-Fábregas, Joan, Delgado, Pilar, Montaner, Joan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Cohort Studies Female Genetic Testing Genotype Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Interleukin-1beta - genetics Logistic Models Male Medical sciences Nervous system (semeiology, syndromes) Neurology Pharmacogenetics Polymorphism, Single Nucleotide - genetics Prospective Studies Retrospective Studies Spain Stroke - drug therapy Stroke - ethnology Stroke - genetics Thrombolytic Therapy Tissue Plasminogen Activator - therapeutic use Treatment Outcome Vascular diseases and vascular malformations of the nervous system von Willebrand Factor - genetics
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