Acyl-CoA binding domain containing 3 (ACBD3) recruits the protein phosphatase PPM1L to ER–Golgi membrane contact sites

► Acyl-CoA binding domain containing 3 (ACBD3) is an interacting partner of PPM1L. ► This association is mediated by a GOLD (Golgi dynamics) domain in ACBD3. ► ACBD3 recruits PPM1L to ER–Golgi membrane contact sites. ► ACBD3 plays a pivotal role in ceramide transport regulation. The metal-dependent...

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Veröffentlicht in:	FEBS letters 2012-09, Vol.586 (19), p.3024-3029
Hauptverfasser:	Shinoda, Yasuharu, Fujita, Kohsuke, Saito, Satoko, Matsui, Hiroyuki, Kanto, Yusuke, Nagaura, Yuko, Fukunaga, Kohji, Tamura, Shinri, Kobayashi, Takayasu
Format:	Artikel
Sprache:	eng
Schlagworte:	ACBD3 acyl-CoA binding domain containing 3 Adaptor Proteins, Signal Transducing - chemistry Adaptor Proteins, Signal Transducing - genetics Adaptor Proteins, Signal Transducing - metabolism Binding Sites CERT endoplasmic reticulum Endoplasmic Reticulum - metabolism FYCO1 FYVE and coiled-coil domain-containing protein 1 GOLD GOLD domain Golgi Apparatus - metabolism Golgi dynamics HEK293 Cells HeLa Cells Humans Membrane Proteins - chemistry Membrane Proteins - genetics Membrane Proteins - metabolism metal-dependent protein phosphatase 1L Models, Biological Models, Molecular Phosphoprotein Phosphatases - chemistry Phosphoprotein Phosphatases - genetics Phosphoprotein Phosphatases - metabolism PPM1L Protein Interaction Domains and Motifs Protein Transport Protein-Serine-Threonine Kinases - chemistry Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Signal Transduction Two-Hybrid System Techniques Vesicular Transport Proteins - chemistry Vesicular Transport Proteins - genetics Vesicular Transport Proteins - metabolism
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