The novel monoclonal antibody HPC2 and N-cadherin distinguish pancreatic ductal adenocarcinoma from cholangiocarcinoma

Summary Metastatic pancreatic ductal adenocarcinoma and primary cholangiocarcinoma are morphologically very similar and, therefore, challenging to distinguish in liver biopsies. The distinction is important because surgical management and prognosis differ significantly. Several immunohistochemical m...

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Veröffentlicht in:	Human pathology 2012-10, Vol.43 (10), p.1583-1589
Hauptverfasser:	Hooper, Jody E., MD, Morgan, Terry K., MD, PhD, Grompe, Markus, MD, Sheppard, Brett C., MD, Troxell, Megan L., MD, PhD, Corless, Christopher L., MD, PhD, Streeter, Philip R., PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal Bile Duct Neoplasms - diagnosis Bile Duct Neoplasms - metabolism Bile Ducts, Intrahepatic - pathology Biological and medical sciences Biomarkers, Tumor - analysis Cadherins - analysis Cadherins - biosynthesis Carcinoma, Pancreatic Ductal - diagnosis Carcinoma, Pancreatic Ductal - metabolism Cholangiocarcinoma Cholangiocarcinoma - diagnosis Cholangiocarcinoma - metabolism Confidence intervals Diagnosis, Differential Dilution Gallbladder Gastroenterology. Liver. Pancreas. Abdomen HPC2 Humans Immunohistochemistry Investigative techniques, diagnostic techniques (general aspects) Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences N-cadherin Neoplasm Proteins - analysis Neoplasm Proteins - biosynthesis Pancreas Pancreatic cancer Pancreatic ductal adenocarcinoma Pancreatic Neoplasms - diagnosis Pancreatic Neoplasms - metabolism Pathology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Statistical analysis Tumors
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