Role of altered rpoB alleles in Bacillus subtilis sporulation and spore resistance to heat, hydrogen peroxide, formaldehyde, and glutaraldehyde
Mutations in the RNA polymerase β-subunit gene rpoB causing resistance to rifampicin (Rif R ) in Bacillus subtilis were previously shown to lead to alterations in the expression of a number of global phenotypes known to be under transcriptional control. To better understand the influence of rpoB mut...
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| Veröffentlicht in: | Archives of microbiology 2012-09, Vol.194 (9), p.759-767 |
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| creator | Moeller, Ralf Vlašić, Ignacija Reitz, Günther Nicholson, Wayne L. |
| description | Mutations in the RNA polymerase β-subunit gene
rpoB
causing resistance to rifampicin (Rif
R
) in
Bacillus subtilis
were previously shown to lead to alterations in the expression of a number of global phenotypes known to be under transcriptional control. To better understand the influence of
rpoB
mutations on sporulation and spore resistance to heat and chemicals, cells and spores of the wild-type and twelve distinct congenic Rif
R
mutant strains of
B. subtilis
were tested. Different levels of glucose catabolite repression during sporulation and spore resistance to heat and chemicals were observed in the Rif
R
mutants, indicating the important role played by the RNA polymerase β-subunit, not only in the catalytic aspect of transcription, but also in the initiation of sporulation and in the spore resistance properties of
B. subtilis
. |
| doi_str_mv | 10.1007/s00203-012-0811-4 |
| format | Article |
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rpoB
causing resistance to rifampicin (Rif
R
) in
Bacillus subtilis
were previously shown to lead to alterations in the expression of a number of global phenotypes known to be under transcriptional control. To better understand the influence of
rpoB
mutations on sporulation and spore resistance to heat and chemicals, cells and spores of the wild-type and twelve distinct congenic Rif
R
mutant strains of
B. subtilis
were tested. Different levels of glucose catabolite repression during sporulation and spore resistance to heat and chemicals were observed in the Rif
R
mutants, indicating the important role played by the RNA polymerase β-subunit, not only in the catalytic aspect of transcription, but also in the initiation of sporulation and in the spore resistance properties of
B. subtilis
.</description><identifier>ISSN: 0302-8933</identifier><identifier>EISSN: 1432-072X</identifier><identifier>DOI: 10.1007/s00203-012-0811-4</identifier><identifier>PMID: 22484477</identifier><identifier>CODEN: AMICCW</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Alleles ; Amino acids ; Anti-Infective Agents - pharmacology ; Astrobiology ; Bacillus subtilis ; Bacillus subtilis - drug effects ; Bacillus subtilis - genetics ; Bacillus subtilis - physiology ; Bacteriology ; Biochemistry ; Biological and medical sciences ; Biomedical and Life Sciences ; Biotechnology ; Cell Biology ; DNA-Directed RNA Polymerases - genetics ; Drug Resistance, Bacterial - genetics ; Ecology ; Enzymes ; Formaldehyde - pharmacology ; Fundamental and applied biological sciences. Psychology ; Gene expression ; Glucose ; Glucose - metabolism ; Glutaral - pharmacology ; Hot Temperature ; Hydrogen peroxide ; Hydrogen Peroxide - pharmacology ; Life Sciences ; Microbial Ecology ; Microbiology ; Miscellaneous ; Mutation ; Original Paper ; RNA polymerase ; Spores, Bacterial - drug effects ; Spores, Bacterial - genetics ; Water - metabolism</subject><ispartof>Archives of microbiology, 2012-09, Vol.194 (9), p.759-767</ispartof><rights>Springer-Verlag 2012</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c501t-178fc5c99de13102a624a378b3efe79b1e28eaf114fa2bc8a43e83a6682ee1763</citedby><cites>FETCH-LOGICAL-c501t-178fc5c99de13102a624a378b3efe79b1e28eaf114fa2bc8a43e83a6682ee1763</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00203-012-0811-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00203-012-0811-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27902,27903,41466,42535,51296</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26238719$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22484477$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Moeller, Ralf</creatorcontrib><creatorcontrib>Vlašić, Ignacija</creatorcontrib><creatorcontrib>Reitz, Günther</creatorcontrib><creatorcontrib>Nicholson, Wayne L.</creatorcontrib><title>Role of altered rpoB alleles in Bacillus subtilis sporulation and spore resistance to heat, hydrogen peroxide, formaldehyde, and glutaraldehyde</title><title>Archives of microbiology</title><addtitle>Arch Microbiol</addtitle><addtitle>Arch Microbiol</addtitle><description>Mutations in the RNA polymerase β-subunit gene
rpoB
causing resistance to rifampicin (Rif
R
) in
Bacillus subtilis
were previously shown to lead to alterations in the expression of a number of global phenotypes known to be under transcriptional control. To better understand the influence of
rpoB
mutations on sporulation and spore resistance to heat and chemicals, cells and spores of the wild-type and twelve distinct congenic Rif
R
mutant strains of
B. subtilis
were tested. Different levels of glucose catabolite repression during sporulation and spore resistance to heat and chemicals were observed in the Rif
R
mutants, indicating the important role played by the RNA polymerase β-subunit, not only in the catalytic aspect of transcription, but also in the initiation of sporulation and in the spore resistance properties of
B. subtilis
.</description><subject>Alleles</subject><subject>Amino acids</subject><subject>Anti-Infective Agents - pharmacology</subject><subject>Astrobiology</subject><subject>Bacillus subtilis</subject><subject>Bacillus subtilis - drug effects</subject><subject>Bacillus subtilis - genetics</subject><subject>Bacillus subtilis - physiology</subject><subject>Bacteriology</subject><subject>Biochemistry</subject><subject>Biological and medical sciences</subject><subject>Biomedical and Life Sciences</subject><subject>Biotechnology</subject><subject>Cell Biology</subject><subject>DNA-Directed RNA Polymerases - genetics</subject><subject>Drug Resistance, Bacterial - genetics</subject><subject>Ecology</subject><subject>Enzymes</subject><subject>Formaldehyde - pharmacology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gene expression</subject><subject>Glucose</subject><subject>Glucose - metabolism</subject><subject>Glutaral - pharmacology</subject><subject>Hot Temperature</subject><subject>Hydrogen peroxide</subject><subject>Hydrogen Peroxide - pharmacology</subject><subject>Life Sciences</subject><subject>Microbial Ecology</subject><subject>Microbiology</subject><subject>Miscellaneous</subject><subject>Mutation</subject><subject>Original Paper</subject><subject>RNA polymerase</subject><subject>Spores, Bacterial - drug effects</subject><subject>Spores, Bacterial - genetics</subject><subject>Water - metabolism</subject><issn>0302-8933</issn><issn>1432-072X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkd9qFDEUh4Modq0-gDcSEMGLjuYk2Unm0hb_QaEgCt4NZ2ZOtinZyZjMgH0KX7nZ7taKIHiV_HK-c5LwMfYcxBsQwrzNQkihKgGyEhag0g_YCrQqycjvD9lKKCEr2yh1xJ7kfCUKaK19zI6k1FZrY1bs15cYiEfHMcyUaOBpiqclBAqUuR_5KfY-hCXzvHSzD75sppiWgLOPI8dxuM3EE2WfZxx74nPkl4TzCb-8HlLc0MgnSvGnH-iEu5i2GAYqpZJ27ZuwzJjuzp6yRw5DpmeH9Zh9-_D-69mn6vzi4-ezd-dVvxYwV2Cs69d90wwECoTEWmpUxnaKHJmmA5KW0AFoh7LrLWpFVmFdW0kEplbH7PV-7pTij4Xy3G597ikEHCkuuQVRN9AYY-1_oEpLIYReF_TlX-hVXNJYPrKjjDSqrqFQsKf6FHNO5Nop-S2m6wK1O7HtXmxbfLU7sa0uPS8Ok5duS8PvjjuTBXh1ADD3GFwqKny-52qprIGmcHLP5VIaN5T-fOK_br8BAjm70w</recordid><startdate>20120901</startdate><enddate>20120901</enddate><creator>Moeller, Ralf</creator><creator>Vlašić, Ignacija</creator><creator>Reitz, Günther</creator><creator>Nicholson, Wayne L.</creator><general>Springer-Verlag</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20120901</creationdate><title>Role of altered rpoB alleles in Bacillus subtilis sporulation and spore resistance to heat, hydrogen peroxide, formaldehyde, and glutaraldehyde</title><author>Moeller, Ralf ; Vlašić, Ignacija ; Reitz, Günther ; Nicholson, Wayne L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c501t-178fc5c99de13102a624a378b3efe79b1e28eaf114fa2bc8a43e83a6682ee1763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Alleles</topic><topic>Amino acids</topic><topic>Anti-Infective Agents - pharmacology</topic><topic>Astrobiology</topic><topic>Bacillus subtilis</topic><topic>Bacillus subtilis - drug effects</topic><topic>Bacillus subtilis - genetics</topic><topic>Bacillus subtilis - physiology</topic><topic>Bacteriology</topic><topic>Biochemistry</topic><topic>Biological and medical sciences</topic><topic>Biomedical and Life Sciences</topic><topic>Biotechnology</topic><topic>Cell Biology</topic><topic>DNA-Directed RNA Polymerases - genetics</topic><topic>Drug Resistance, Bacterial - genetics</topic><topic>Ecology</topic><topic>Enzymes</topic><topic>Formaldehyde - pharmacology</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gene expression</topic><topic>Glucose</topic><topic>Glucose - metabolism</topic><topic>Glutaral - pharmacology</topic><topic>Hot Temperature</topic><topic>Hydrogen peroxide</topic><topic>Hydrogen Peroxide - pharmacology</topic><topic>Life Sciences</topic><topic>Microbial Ecology</topic><topic>Microbiology</topic><topic>Miscellaneous</topic><topic>Mutation</topic><topic>Original Paper</topic><topic>RNA polymerase</topic><topic>Spores, Bacterial - drug effects</topic><topic>Spores, Bacterial - genetics</topic><topic>Water - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Moeller, Ralf</creatorcontrib><creatorcontrib>Vlašić, Ignacija</creatorcontrib><creatorcontrib>Reitz, Günther</creatorcontrib><creatorcontrib>Nicholson, Wayne L.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Moeller, Ralf</au><au>Vlašić, Ignacija</au><au>Reitz, Günther</au><au>Nicholson, Wayne L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Role of altered rpoB alleles in Bacillus subtilis sporulation and spore resistance to heat, hydrogen peroxide, formaldehyde, and glutaraldehyde</atitle><jtitle>Archives of microbiology</jtitle><stitle>Arch Microbiol</stitle><addtitle>Arch Microbiol</addtitle><date>2012-09-01</date><risdate>2012</risdate><volume>194</volume><issue>9</issue><spage>759</spage><epage>767</epage><pages>759-767</pages><issn>0302-8933</issn><eissn>1432-072X</eissn><coden>AMICCW</coden><abstract>Mutations in the RNA polymerase β-subunit gene
rpoB
causing resistance to rifampicin (Rif
R
) in
Bacillus subtilis
were previously shown to lead to alterations in the expression of a number of global phenotypes known to be under transcriptional control. To better understand the influence of
rpoB
mutations on sporulation and spore resistance to heat and chemicals, cells and spores of the wild-type and twelve distinct congenic Rif
R
mutant strains of
B. subtilis
were tested. Different levels of glucose catabolite repression during sporulation and spore resistance to heat and chemicals were observed in the Rif
R
mutants, indicating the important role played by the RNA polymerase β-subunit, not only in the catalytic aspect of transcription, but also in the initiation of sporulation and in the spore resistance properties of
B. subtilis
.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>22484477</pmid><doi>10.1007/s00203-012-0811-4</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0302-8933 |
| ispartof | Archives of microbiology, 2012-09, Vol.194 (9), p.759-767 |
| issn | 0302-8933 1432-072X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1069197788 |
| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Alleles Amino acids Anti-Infective Agents - pharmacology Astrobiology Bacillus subtilis Bacillus subtilis - drug effects Bacillus subtilis - genetics Bacillus subtilis - physiology Bacteriology Biochemistry Biological and medical sciences Biomedical and Life Sciences Biotechnology Cell Biology DNA-Directed RNA Polymerases - genetics Drug Resistance, Bacterial - genetics Ecology Enzymes Formaldehyde - pharmacology Fundamental and applied biological sciences. Psychology Gene expression Glucose Glucose - metabolism Glutaral - pharmacology Hot Temperature Hydrogen peroxide Hydrogen Peroxide - pharmacology Life Sciences Microbial Ecology Microbiology Miscellaneous Mutation Original Paper RNA polymerase Spores, Bacterial - drug effects Spores, Bacterial - genetics Water - metabolism |
| title | Role of altered rpoB alleles in Bacillus subtilis sporulation and spore resistance to heat, hydrogen peroxide, formaldehyde, and glutaraldehyde |
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