Impact of the -174G/C interleukin-6 (IL-6) gene polymorphism on the risk of paediatric ischemic stroke, its symptoms and outcome

Ischemic stroke remains one of the top ten causes of death in children. There is evidence for the role of pro-inflammatory cytokines, such as IL-6 and the -174G>C promoter polymorphism of the IL-6 gene, in the occurrence and outcome of stroke in adults. The aim of the present study was to determi...

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Veröffentlicht in:	Folia neuropathologica 2012, Vol.50 (2), p.147-151
Hauptverfasser:	Balcerzyk, Anna, Nowak, Marta, Kopyta, Ilona, Emich-Widera, Ewa, Pilarska, Ewa, Pienczk-Ręcławowicz, Karolina, Kaciński, Marek, Wendorff, Janusz, Zak, Iwona
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Brain Ischemia - genetics Child Child, Preschool Children Data processing Epilepsy Female Gene polymorphism Genetic Predisposition to Disease - genetics Genotype Guanylate cyclase Homozygotes Humans Infant Inflammation Interleukin 6 Interleukin-6 - genetics Ischemia Linkage disequilibrium Male Neurotransmission Pediatrics Polymorphism, Restriction Fragment Length Polymorphism, Single Nucleotide Risk Factors Statistics Stroke Stroke - genetics
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