Opposite and redundant roles of the two Drosophila perilipins in lipid mobilization

Lipid droplets are the main lipid storage sites in cells. Lipid droplet homeostasis is regulated by the surface accessibility of lipases. Mammalian adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) are two key lipases for basal and stimulated lipolysis, respectively. Perilipins,...

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Veröffentlicht in:	Journal of cell science 2012-08, Vol.125 (Pt 15), p.3568-3577
Hauptverfasser:	Bi, Junfeng, Xiang, Yanhui, Chen, Haiyang, Liu, Zhonghua, Grönke, Sebastian, Kühnlein, Ronald P, Huang, Xun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Drosophila - genetics Drosophila - metabolism Drosophila Proteins - genetics Drosophila Proteins - metabolism Lipid Metabolism - physiology Oxidoreductases, N-Demethylating - genetics Oxidoreductases, N-Demethylating - metabolism Protein Transport Sterol Esterase - genetics Sterol Esterase - metabolism
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