The Neutrophilic Inflammatory Phenotype Is Associated With Systemic Inflammation in Asthma

Background The role of systemic inflammation in asthma is unclear. The aim of this study was to compare systemic inflammation in subjects with stable asthma, categorized by airway inflammatory phenotype, with healthy control subjects. Methods Adults with stable asthma (n = 152) and healthy control s...

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Veröffentlicht in:	Chest 2012-07, Vol.142 (1), p.86-93
Hauptverfasser:	Wood, Lisa G., PhD, Baines, Katherine J., PhD, Fu, Juanjuan, MD, Scott, Hayley A., BND, Gibson, Peter G., MBBS
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Asthma - classification Asthma - metabolism Asthma - pathology Biological and medical sciences Biomarkers - metabolism C-Reactive Protein - metabolism Cardiology. Vascular system Case-Control Studies Chronic obstructive pulmonary disease, asthma Female Humans Inflammation - pathology Interleukin-6 - blood Interleukin-8 - metabolism Leukocyte Elastase - metabolism Male Medical sciences Middle Aged Neutrophils - pathology Phenotype Pneumology Pulmonary/Respiratory Sputum - metabolism Tumor Necrosis Factor-alpha - blood
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