Comparison between initial and chronic response to clopidogrel therapy after coronary stenting for acute coronary syndrome and influence on clinical outcomes

Background Studies have addressed the benefit of tailored therapy based on initial response to clopidogrel loading dose. However, the appropriate timing for platelet testing remains uncertain. Methods The present study was performed to compare initial clopidogrel response after 600 mg loading dose a...

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Veröffentlicht in:	The American heart journal 2012-09, Vol.164 (3), p.327-333
Hauptverfasser:	Cuisset, Thomas, MD, PhD, Quilici, Jacques, MD, Loosveld, Marie, MD, Gaborit, Bénédicte, MD, Grosdidier, Charlotte, MD, Fourcade, Laurent, MD, Gil, Jean-Marie, MD, Moro, Pierre Julien, MD, Morange, Pierre-Emmanuel, MD, PhD, Bonnet, Jean-Louis, MD, PhD, Alessi, Marie-Christine, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Coronary Syndrome - drug therapy Acute Coronary Syndrome - surgery Acute coronary syndromes Aged Biological and medical sciences Cardiology. Vascular system Cardiovascular Cell Adhesion Molecules - drug effects Cell Adhesion Molecules - metabolism Clinical outcomes Coronary heart disease Coronary vessels Dose-Response Relationship, Drug Drug therapy Female Follow-Up Studies Heart Heart attacks Humans Incidence Male Medical sciences Microfilament Proteins - drug effects Microfilament Proteins - metabolism Middle Aged Myocarditis. Cardiomyopathies Percutaneous Coronary Intervention Phosphoproteins - drug effects Phosphoproteins - metabolism Platelet Aggregation - drug effects Platelet Aggregation Inhibitors - administration & dosage Postoperative Period Prospective Studies Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Stents Studies Ticlopidine - administration & dosage Ticlopidine - analogs & derivatives Treatment Outcome
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