An improved LC–S/MS method for the quantitation of adenosine concentration in mice brain microdialysates

► LC/MS/MS method is developed for the quantitative analysis of adenosine in dialysates. ► A column switching method is developed to reach high sensitivity. ► The method is applied to quantify adenosine in mice microdialysis samples. A sensitive liquid chromatography tandem mass spectrometry (LC–MS/...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2012-11, Vol.70, p.563-566
Hauptverfasser:	Carrozzo, Marina M., Troisi, Luigino, Cannazza, Giuseppe, Cazzato, Addolorata S., Braghiroli, Daniela, Parenti, Carlo, Guiducci, Stefania, Zoli, Michele
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Adenosine - metabolism Analysis Analytical, structural and metabolic biochemistry Animals Biological and medical sciences brain Brain - drug effects Brain - metabolism Calibration Chromatography, Liquid - standards Column-switching Fundamental and applied biological sciences. Psychology General pharmacology Kainic Acid - pharmacology LC–MS/MS Limit of Detection Linear Models liquid chromatography Medical sciences Mice Microdialysis Pharmacology. Drug treatments Reference Standards Reproducibility of Results Sensitivity and Specificity Spectrometry, Mass, Electrospray Ionization tandem mass spectrometry Tandem Mass Spectrometry - standards Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!