Characterization of phenolic compounds and antinociceptive activity of Sempervivum tectorum L. leaf juice

Sempervivum tectorum L. (houseleek) leaf juice has been known as a traditional herbal remedy. The aim of the present study was the chemical characterization of its phenolic compounds and to develop quantitation methods for its main flavonol glycoside, as well as to evaluate its antinociceptive activ...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2012-11, Vol.70, p.143-150
Hauptverfasser:	Alberti, Ágnes, Béni, Szabolcs, Lackó, Erzsébet, Riba, Pál, Al-Khrasani, Mahmoud, Kéry, Ágnes
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic Acid acids Analgesics - chemistry Analgesics - isolation & purification Analgesics - pharmacology Analysis Analytical, structural and metabolic biochemistry Animals Behavior, Animal - drug effects Biological and medical sciences Calibration Chromatography, High Pressure Liquid - standards Crassulaceae Crassulaceae - chemistry Disease Models, Animal Flavonol Freeze Drying Fundamental and applied biological sciences. Psychology General pharmacology glycosides Glycosides - pharmacology high performance liquid chromatography Houseleek ionization juices kaempferol Kaempferols - pharmacology LC–MS leaves Magnetic Resonance Spectroscopy - standards Male Medical sciences Mice Molecular Structure nuclear magnetic resonance spectroscopy pain Pain - chemically induced Pain - prevention & control Pharmacology. Drug treatments Phenolic acid phenolic compounds Phenols - chemistry Phenols - isolation & purification Phenols - pharmacology Plant Extracts - chemistry Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Leaves quantitative analysis Reference Standards Reproducibility of Results Sempervivum tectorum Sempervivum tectorum L Spectrometry, Mass, Electrospray Ionization - standards tandem mass spectrometry Tandem Mass Spectrometry - standards
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