Role of French teams in the development of clinical and translational research in radiation oncology
Many clinical studies have showed the key role of radiotherapy in anticancer treatment strategy. Radiations are delivered alone or in combination with systemic therapies. In recent years, the main goal of all clinical developments has focused on improving clinical benefit, with an increased tumour c...
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| Veröffentlicht in: | Cancer radiothérapie 2012-09, Vol.16 (5-6), p.386-391 |
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| container_title | Cancer radiothérapie |
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| creator | Azria, D Ardiet, J-M Chauvet, B Denis, F Eschwège, F Hennequin, C Lartigau, E Rocher, F Mahé, M-A Maingon, P Mazeron, J-J Metayer, Y Peiffert, D Thureau, S Mornex, F |
| description | Many clinical studies have showed the key role of radiotherapy in anticancer treatment strategy. Radiations are delivered alone or in combination with systemic therapies. In recent years, the main goal of all clinical developments has focused on improving clinical benefit, with an increased tumour control and a higher normal tissue protection. This research was designed to reduce local recurrences, to increase recurrence-free or overall survival and to decrease acute and late effects. Technological and biological evolutions (or revolutions) accompanied clinicians to improve clinical benefit, namely with strong progress in radiology and better understanding of radiobiology, particularly at the molecular level. Differences in tumour and normal tissues radiosensitivity are nowadays integrated in daily clinical practice of radiation oncologists. The current report details the last 5-year developments of clinical and translational research in radiation oncology, especially the role of French teams in the development of personalized treatment. |
| doi_str_mv | 10.1016/j.canrad.2012.05.009 |
| format | Article |
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Radiations are delivered alone or in combination with systemic therapies. In recent years, the main goal of all clinical developments has focused on improving clinical benefit, with an increased tumour control and a higher normal tissue protection. This research was designed to reduce local recurrences, to increase recurrence-free or overall survival and to decrease acute and late effects. Technological and biological evolutions (or revolutions) accompanied clinicians to improve clinical benefit, namely with strong progress in radiology and better understanding of radiobiology, particularly at the molecular level. Differences in tumour and normal tissues radiosensitivity are nowadays integrated in daily clinical practice of radiation oncologists. 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| fulltext | fulltext |
| identifier | EISSN: 1769-6658 |
| ispartof | Cancer radiothérapie, 2012-09, Vol.16 (5-6), p.386-391 |
| issn | 1769-6658 |
| language | fre |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Biomedical Research Humans Radiation Oncology Radiosurgery Radiotherapy Dosage Radiotherapy, Image-Guided Radiotherapy, Intensity-Modulated Translational Medical Research |
| title | Role of French teams in the development of clinical and translational research in radiation oncology |
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