Atypical mucocutaneous involvement with Leishmania donovani
Mucocutaneous leishmaniasis has rarely been reported from India. The usual causative organisms of this infection are Leishmania braziliensis and L. tropica. Another species, L. donovani, which usually causes visceral leishmaniasis, has recently been reported to cause mucocutaneous disease in a few p...
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Veröffentlicht in: | The National medical journal of India 2012-05, Vol.25 (3), p.148-150 |
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creator | Pulimood, S A Rupali, P Ajjampur, S S R Thomas, M Mehrotra, S Sundar, S |
description | Mucocutaneous leishmaniasis has rarely been reported from India. The usual causative organisms of this infection are Leishmania braziliensis and L. tropica. Another species, L. donovani, which usually causes visceral leishmaniasis, has recently been reported to cause mucocutaneous disease in a few patients from Sri Lanka. We report two patients who had undiagnosed chronic skin lesions for several years. Skin biopsies revealed Leishmania and the species was characterized as L. donovani in both patients. There was considerable improvement in the skin lesions following treatment with liposomal amphotericin B. |
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The usual causative organisms of this infection are Leishmania braziliensis and L. tropica. Another species, L. donovani, which usually causes visceral leishmaniasis, has recently been reported to cause mucocutaneous disease in a few patients from Sri Lanka. We report two patients who had undiagnosed chronic skin lesions for several years. Skin biopsies revealed Leishmania and the species was characterized as L. donovani in both patients. 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The usual causative organisms of this infection are Leishmania braziliensis and L. tropica. Another species, L. donovani, which usually causes visceral leishmaniasis, has recently been reported to cause mucocutaneous disease in a few patients from Sri Lanka. We report two patients who had undiagnosed chronic skin lesions for several years. Skin biopsies revealed Leishmania and the species was characterized as L. donovani in both patients. There was considerable improvement in the skin lesions following treatment with liposomal amphotericin B.</description><subject>Adult</subject><subject>Amphotericin B - therapeutic use</subject><subject>Antiprotozoal Agents - therapeutic use</subject><subject>Bhutan - ethnology</subject><subject>Humans</subject><subject>India</subject><subject>Leishmania donovani - isolation & purification</subject><subject>Leishmaniasis, Cutaneous - drug therapy</subject><subject>Leishmaniasis, Cutaneous - parasitology</subject><subject>Leishmaniasis, Cutaneous - pathology</subject><subject>Leishmaniasis, Mucocutaneous - drug therapy</subject><subject>Leishmaniasis, Mucocutaneous - parasitology</subject><subject>Leishmaniasis, Mucocutaneous - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><issn>0970-258X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1jztrwzAUhTW0NGnav1A8djHoYUsWnULoCwxdWuhmruQbomJZriW75N_XkGQ6Z_g4jyuyplrRnJfV94rcxvhDqRSsZDdkxbmWgmu-Jk_bdBychS7zkw12StBjmGLm-jl0M3rsU_bn0iGr0cWDh95B1oY-zIu7I9d76CLen3VDvl6eP3dvef3x-r7b1vnAGUu54UwvdZbvS2OqtiilbKGi1iAHKCVQhcooyRQIU2nVciatKVAVtjBMCCs25PGUO4zhd8KYGu-ixa47bW0YFZrTikq1oA9ndDIe22YYnYfx2FwOi39RBVFQ</recordid><startdate>201205</startdate><enddate>201205</enddate><creator>Pulimood, S A</creator><creator>Rupali, P</creator><creator>Ajjampur, S S R</creator><creator>Thomas, M</creator><creator>Mehrotra, S</creator><creator>Sundar, S</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201205</creationdate><title>Atypical mucocutaneous involvement with Leishmania donovani</title><author>Pulimood, S A ; Rupali, P ; Ajjampur, S S R ; Thomas, M ; Mehrotra, S ; Sundar, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p211t-b219963c2f5bb8d4566da80cbe2aa56a07e7b7617a3b897d216cb4e74c4b133c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Amphotericin B - therapeutic use</topic><topic>Antiprotozoal Agents - therapeutic use</topic><topic>Bhutan - ethnology</topic><topic>Humans</topic><topic>India</topic><topic>Leishmania donovani - isolation & purification</topic><topic>Leishmaniasis, Cutaneous - drug therapy</topic><topic>Leishmaniasis, Cutaneous - parasitology</topic><topic>Leishmaniasis, Cutaneous - pathology</topic><topic>Leishmaniasis, Mucocutaneous - drug therapy</topic><topic>Leishmaniasis, Mucocutaneous - parasitology</topic><topic>Leishmaniasis, Mucocutaneous - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pulimood, S A</creatorcontrib><creatorcontrib>Rupali, P</creatorcontrib><creatorcontrib>Ajjampur, S S R</creatorcontrib><creatorcontrib>Thomas, M</creatorcontrib><creatorcontrib>Mehrotra, S</creatorcontrib><creatorcontrib>Sundar, S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The National medical journal of India</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pulimood, S A</au><au>Rupali, P</au><au>Ajjampur, S S R</au><au>Thomas, M</au><au>Mehrotra, S</au><au>Sundar, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Atypical mucocutaneous involvement with Leishmania donovani</atitle><jtitle>The National medical journal of India</jtitle><addtitle>Natl Med J India</addtitle><date>2012-05</date><risdate>2012</risdate><volume>25</volume><issue>3</issue><spage>148</spage><epage>150</epage><pages>148-150</pages><issn>0970-258X</issn><abstract>Mucocutaneous leishmaniasis has rarely been reported from India. 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subjects | Adult Amphotericin B - therapeutic use Antiprotozoal Agents - therapeutic use Bhutan - ethnology Humans India Leishmania donovani - isolation & purification Leishmaniasis, Cutaneous - drug therapy Leishmaniasis, Cutaneous - parasitology Leishmaniasis, Cutaneous - pathology Leishmaniasis, Mucocutaneous - drug therapy Leishmaniasis, Mucocutaneous - parasitology Leishmaniasis, Mucocutaneous - pathology Male Middle Aged |
title | Atypical mucocutaneous involvement with Leishmania donovani |
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