The Effects of Poloxamer-188 on Left Ventricular Function in Chronic Heart Failure After Myocardial Infarction

BACKGROUND:Poloxamer-188 (P-188) is a biological membrane sealant that prevents the unregulated entry of Ca into cardiomyocytes and has been shown to have the ability to act as a membrane-repair agent in isolated cardiac myocytes. The purpose of this study was to determine if treatment with P-188 wo...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 2012-09, Vol.60 (3), p.293-298
Hauptverfasser:	Juneman, Elizabeth B, Saleh, Laith, Lancaster, Jordan J, Thai, Hoang M, Markham, Bruce, Goldman, Steven
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Heart Failure - drug therapy Heart Failure - physiopathology Male Myocardial Infarction - drug therapy Myocardial Infarction - physiopathology Poloxamer - pharmacology Poloxamer - therapeutic use Rats Rats, Sprague-Dawley Treatment Outcome Ventricular Function, Left - drug effects Ventricular Function, Left - physiology
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