The Prereplication Complex Recruits XEco2 to Chromatin to Promote Cohesin Acetylation in Xenopus Egg Extracts

Sister chromatids are held together by the ring-shaped cohesin complex, which is loaded onto chromosomes before DNA replication. Cohesion between sister chromosomes is established during DNA replication, and it requires acetylation of the Smc3 subunit of cohesin by evolutionally conserved cohesin ac...

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Veröffentlicht in:	Current biology 2012-06, Vol.22 (11), p.977-988
Hauptverfasser:	Higashi, Torahiko L., Ikeda, Megumi, Tanaka, Hiroshi, Nakagawa, Takuro, Bando, Masashige, Shirahige, Katsuhiko, Kubota, Yumiko, Takisawa, Haruhiko, Masukata, Hisao, Takahashi, Tatsuro S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Acetyltransferase acetyltransferases Acetyltransferases - metabolism Amino Acid Sequence Animals Cell Cycle Proteins - metabolism chromatids Chromatids - physiology Chromatin Chromatin - metabolism Chromosomal Proteins, Non-Histone - metabolism Chromosomes cohesin Cohesins cohesion DNA DNA biosynthesis DNA Replication eggs Evolution Female Male Molecular Sequence Data Ovum - metabolism Proliferating Cell Nuclear Antigen - metabolism Protein Serine-Threonine Kinases - metabolism Recruitment Replication sister chromatids vertebrates Xenopus Xenopus Proteins - metabolism
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