The NtrY/X two-component system of Brucella spp. acts as a redox sensor and regulates the expression of nitrogen respiration enzymes

Summary Brucella spp. are facultative intracellular bacteria pathogenic for many mammalian species including humans, causing a disease called brucellosis. Learning how Brucella adapts to its intracellular niche is crucial for understanding its pathogenesis mechanism, allowing for the development of...

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Veröffentlicht in:	Molecular microbiology 2012-07, Vol.85 (1), p.39-50
Hauptverfasser:	Carrica, Mariela del Carmen, Fernandez, Ignacio, Martí, Marcelo Adrián, Paris, Gastón, Goldbaum, Fernando Alberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological Animals Bacteriology Biological and medical sciences Brucella abortus Brucella abortus - enzymology Brucella abortus - genetics Cell Line Denitrification Enzymes Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation, Bacterial Gram-negative bacteria Heme - metabolism Histidine Kinase Hypoxia Kinases Mice Microbiology Miscellaneous Nitrogen - metabolism Operon Oxidation-Reduction Oxygen - metabolism Pathogenesis Phosphorylation Promoter Regions, Genetic Protein Kinases - genetics Protein Kinases - metabolism Signal Transduction
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