New insights into the pathogenesis of Behçet's disease

Abstract Behçet's disease (BD) is a recurrent systemic inflammatory disorder of unknown origin characterized by oral and genital mucous ulcer, uveitis, and skin lesions. Involvement of large vessels, central nervous system (CNS), gastrointestinal tract and thrombotic events are less frequent bu...

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Veröffentlicht in:	Autoimmunity reviews 2012-08, Vol.11 (10), p.687-698
Hauptverfasser:	Pineton de Chambrun, Marc, Wechsler, Bertrand, Geri, Guillaume, Cacoub, Patrice, Saadoun, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Autoantibodies - biosynthesis Autoimmune diseases Behcet Syndrome - genetics Behcet Syndrome - immunology Behcet Syndrome - pathology Behcet's syndrome Behçet's disease CD8 antigen Central nervous system Cytotoxicity Gastrointestinal tract Genetic Genetic Predisposition to Disease Helper cells HLA-B51 Antigen - physiology Homeostasis Humans IL-10 IL-12 IL-23 Immune system Immunoregulation Inflammation Inflammation - genetics Inflammation - immunology Inflammation - pathology Inflammatory diseases Leukocytes (neutrophilic) Lymphocytes T Major histocompatibility complex Pathogenesis Receptors, Antigen, T-Cell, gamma-delta - physiology Recurrence Reviews Single-nucleotide polymorphism Skin diseases T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - metabolism T-Lymphocyte Subsets - pathology Th17 Ulcers Uveitis Vasculitis
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