Sodium butyrate induces the production of cyclooxygenases and prostaglandin E sub(2) in ROS 17/2.8 osteoblastic cells

Sodium butyrate (butyric acid; BA) is a major metabolic by-product of the anaerobic periodontopathic bacteria present in subgingival plaque. We examined the effects of BA and/or indomethacin on cell proliferation, the expression of cyclooxygenases (COXs), prostaglandin (PG) receptors (EP1-4), extrac...

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Veröffentlicht in:	Archives of oral biology 2011-07, Vol.56 (7), p.678-686
Hauptverfasser:	Takafumi IIda, Takafumi IIda, Kawato, Takayuki, Tanaka, Hideki, Tanabe, Natsuko, Nakai, Kumiko, Zhao, Ning, Suzuki, Naoto, Ochiai, Kuniyasu, Maeno, Masao
Format:	Artikel
Sprache:	eng
Schlagworte:	Autocrine signalling Butyric acid Cell culture Cell proliferation Collagen (type I) Cyclooxygenase-1 Cyclooxygenase-2 Enzyme-linked immunosorbent assay Extracellular matrix Indomethacin mRNA Osteoblasts Osteopontin Plaques Polymerase chain reaction Prostaglandin E2 Sodium butyrate Western blotting
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