Multi-frequency low-dose intravenous iron on oxidative stress in maintenance hemodialysis patients
To investigate the effect of different intravenous iron treatment regimens on anemia and oxidative stress in maintenance hemodialysis (MHD) patients. A total of 58 MHD patients were randomly divided into a multi-frequency low-dose intravenous iron group (iron sucrose 25 mg, twice a week for 8 weeks,...
Gespeichert in:
| Veröffentlicht in: | Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban 2012-08, Vol.37 (8), p.844-848 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | chi |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 848 |
|---|---|
| container_issue | 8 |
| container_start_page | 844 |
| container_title | Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban |
| container_volume | 37 |
| creator | Yin, Li Chen, Xing Chen, Junxiang Cheng, Meichu Peng, Youming Yang, Lijun |
| description | To investigate the effect of different intravenous iron treatment regimens on anemia and oxidative stress in maintenance hemodialysis (MHD) patients.
A total of 58 MHD patients were randomly divided into a multi-frequency low-dose intravenous iron group (iron sucrose 25 mg, twice a week for 8 weeks, n=19), a less-frequency regular-dose intravenous iron group (iron sucrose 100 mg, once every two weeks for 8 weeks, n=19), and a non-iron group (n=20). Another 20 healthy people served as a control group (n=20). The changes of hemoglobin (Hb), hematocrit (HCT), serum ferritin (SF) and transferrin saturation (TSAT), as well as the oxidative stress parameters of malon-dialdehyde (MDA), superoxide dismutase (SOD) and myeloperoxidase (MPO) were detected before and after the treatment.
After 8 weeks, compared with the non-iron group, the levels of Hb, HCT, SF and TSAT in the two iron groups were significantly elevated (P0.05). After the single dialysis, |
| doi_str_mv | 10.3969/j.issn.1672-7347.2012.08.015 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1038591392</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1038591392</sourcerecordid><originalsourceid>FETCH-LOGICAL-p126t-411071e2214d5451b9f2722a6adb987033bfa8e62810456f59015aa4a29afe223</originalsourceid><addsrcrecordid>eNo9kE1Lw0AQhveg2KL9C7IHD14S9zObOUrxCype9BwmzQRXkk3MJtX-e1OswsDAvM8MPMPYlRSphgxuPlIfY0hl5lTitHGpElKlIk-FtCds-T9fsFWMvhQCAHSWuzO2UAqsAQlLVj5PzeiTeqDPicJ2z5vuK6m6SNyHccAdhW6K3A9d4If69hWOfkc8jgPFOQi8xZmkgGFL_J3arvLY7KOPvJ9JCmO8YKc1NpFWx37O3u7vXtePyebl4Wl9u0l6qbIxMVIKJ0kpaSprrCyhVk4pzLAqIXdC67LGnDKVS2FsVluYPRENKsB6XtPn7Pr3bj90s0wci9bHLTUNBpolCil0bkFqOKCXR3QqW6qKfvAtDvvi7y_6BwrEaFY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1038591392</pqid></control><display><type>article</type><title>Multi-frequency low-dose intravenous iron on oxidative stress in maintenance hemodialysis patients</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Yin, Li ; Chen, Xing ; Chen, Junxiang ; Cheng, Meichu ; Peng, Youming ; Yang, Lijun</creator><creatorcontrib>Yin, Li ; Chen, Xing ; Chen, Junxiang ; Cheng, Meichu ; Peng, Youming ; Yang, Lijun</creatorcontrib><description>To investigate the effect of different intravenous iron treatment regimens on anemia and oxidative stress in maintenance hemodialysis (MHD) patients.
A total of 58 MHD patients were randomly divided into a multi-frequency low-dose intravenous iron group (iron sucrose 25 mg, twice a week for 8 weeks, n=19), a less-frequency regular-dose intravenous iron group (iron sucrose 100 mg, once every two weeks for 8 weeks, n=19), and a non-iron group (n=20). Another 20 healthy people served as a control group (n=20). The changes of hemoglobin (Hb), hematocrit (HCT), serum ferritin (SF) and transferrin saturation (TSAT), as well as the oxidative stress parameters of malon-dialdehyde (MDA), superoxide dismutase (SOD) and myeloperoxidase (MPO) were detected before and after the treatment.
After 8 weeks, compared with the non-iron group, the levels of Hb, HCT, SF and TSAT in the two iron groups were significantly elevated (P<0.01), but there was no difference between the two iron groups (P>0.05). After the single dialysis,</description><identifier>ISSN: 1672-7347</identifier><identifier>DOI: 10.3969/j.issn.1672-7347.2012.08.015</identifier><identifier>PMID: 22954919</identifier><language>chi</language><publisher>China</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anemia - drug therapy ; Anemia - etiology ; Female ; Ferric Compounds - administration & dosage ; Glucaric Acid ; Humans ; Injections, Intravenous ; Kidney Failure, Chronic - complications ; Kidney Failure, Chronic - drug therapy ; Male ; Middle Aged ; Oxidative Stress - drug effects ; Renal Dialysis ; Sucrose - administration & dosage ; Young Adult</subject><ispartof>Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban, 2012-08, Vol.37 (8), p.844-848</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22954919$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yin, Li</creatorcontrib><creatorcontrib>Chen, Xing</creatorcontrib><creatorcontrib>Chen, Junxiang</creatorcontrib><creatorcontrib>Cheng, Meichu</creatorcontrib><creatorcontrib>Peng, Youming</creatorcontrib><creatorcontrib>Yang, Lijun</creatorcontrib><title>Multi-frequency low-dose intravenous iron on oxidative stress in maintenance hemodialysis patients</title><title>Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban</title><addtitle>Zhong Nan Da Xue Xue Bao Yi Xue Ban</addtitle><description>To investigate the effect of different intravenous iron treatment regimens on anemia and oxidative stress in maintenance hemodialysis (MHD) patients.
A total of 58 MHD patients were randomly divided into a multi-frequency low-dose intravenous iron group (iron sucrose 25 mg, twice a week for 8 weeks, n=19), a less-frequency regular-dose intravenous iron group (iron sucrose 100 mg, once every two weeks for 8 weeks, n=19), and a non-iron group (n=20). Another 20 healthy people served as a control group (n=20). The changes of hemoglobin (Hb), hematocrit (HCT), serum ferritin (SF) and transferrin saturation (TSAT), as well as the oxidative stress parameters of malon-dialdehyde (MDA), superoxide dismutase (SOD) and myeloperoxidase (MPO) were detected before and after the treatment.
After 8 weeks, compared with the non-iron group, the levels of Hb, HCT, SF and TSAT in the two iron groups were significantly elevated (P<0.01), but there was no difference between the two iron groups (P>0.05). After the single dialysis,</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anemia - drug therapy</subject><subject>Anemia - etiology</subject><subject>Female</subject><subject>Ferric Compounds - administration & dosage</subject><subject>Glucaric Acid</subject><subject>Humans</subject><subject>Injections, Intravenous</subject><subject>Kidney Failure, Chronic - complications</subject><subject>Kidney Failure, Chronic - drug therapy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Oxidative Stress - drug effects</subject><subject>Renal Dialysis</subject><subject>Sucrose - administration & dosage</subject><subject>Young Adult</subject><issn>1672-7347</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE1Lw0AQhveg2KL9C7IHD14S9zObOUrxCype9BwmzQRXkk3MJtX-e1OswsDAvM8MPMPYlRSphgxuPlIfY0hl5lTitHGpElKlIk-FtCds-T9fsFWMvhQCAHSWuzO2UAqsAQlLVj5PzeiTeqDPicJ2z5vuK6m6SNyHccAdhW6K3A9d4If69hWOfkc8jgPFOQi8xZmkgGFL_J3arvLY7KOPvJ9JCmO8YKc1NpFWx37O3u7vXtePyebl4Wl9u0l6qbIxMVIKJ0kpaSprrCyhVk4pzLAqIXdC67LGnDKVS2FsVluYPRENKsB6XtPn7Pr3bj90s0wci9bHLTUNBpolCil0bkFqOKCXR3QqW6qKfvAtDvvi7y_6BwrEaFY</recordid><startdate>201208</startdate><enddate>201208</enddate><creator>Yin, Li</creator><creator>Chen, Xing</creator><creator>Chen, Junxiang</creator><creator>Cheng, Meichu</creator><creator>Peng, Youming</creator><creator>Yang, Lijun</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201208</creationdate><title>Multi-frequency low-dose intravenous iron on oxidative stress in maintenance hemodialysis patients</title><author>Yin, Li ; Chen, Xing ; Chen, Junxiang ; Cheng, Meichu ; Peng, Youming ; Yang, Lijun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p126t-411071e2214d5451b9f2722a6adb987033bfa8e62810456f59015aa4a29afe223</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2012</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anemia - drug therapy</topic><topic>Anemia - etiology</topic><topic>Female</topic><topic>Ferric Compounds - administration & dosage</topic><topic>Glucaric Acid</topic><topic>Humans</topic><topic>Injections, Intravenous</topic><topic>Kidney Failure, Chronic - complications</topic><topic>Kidney Failure, Chronic - drug therapy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Oxidative Stress - drug effects</topic><topic>Renal Dialysis</topic><topic>Sucrose - administration & dosage</topic><topic>Young Adult</topic><toplevel>online_resources</toplevel><creatorcontrib>Yin, Li</creatorcontrib><creatorcontrib>Chen, Xing</creatorcontrib><creatorcontrib>Chen, Junxiang</creatorcontrib><creatorcontrib>Cheng, Meichu</creatorcontrib><creatorcontrib>Peng, Youming</creatorcontrib><creatorcontrib>Yang, Lijun</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yin, Li</au><au>Chen, Xing</au><au>Chen, Junxiang</au><au>Cheng, Meichu</au><au>Peng, Youming</au><au>Yang, Lijun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multi-frequency low-dose intravenous iron on oxidative stress in maintenance hemodialysis patients</atitle><jtitle>Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban</jtitle><addtitle>Zhong Nan Da Xue Xue Bao Yi Xue Ban</addtitle><date>2012-08</date><risdate>2012</risdate><volume>37</volume><issue>8</issue><spage>844</spage><epage>848</epage><pages>844-848</pages><issn>1672-7347</issn><abstract>To investigate the effect of different intravenous iron treatment regimens on anemia and oxidative stress in maintenance hemodialysis (MHD) patients.
A total of 58 MHD patients were randomly divided into a multi-frequency low-dose intravenous iron group (iron sucrose 25 mg, twice a week for 8 weeks, n=19), a less-frequency regular-dose intravenous iron group (iron sucrose 100 mg, once every two weeks for 8 weeks, n=19), and a non-iron group (n=20). Another 20 healthy people served as a control group (n=20). The changes of hemoglobin (Hb), hematocrit (HCT), serum ferritin (SF) and transferrin saturation (TSAT), as well as the oxidative stress parameters of malon-dialdehyde (MDA), superoxide dismutase (SOD) and myeloperoxidase (MPO) were detected before and after the treatment.
After 8 weeks, compared with the non-iron group, the levels of Hb, HCT, SF and TSAT in the two iron groups were significantly elevated (P<0.01), but there was no difference between the two iron groups (P>0.05). After the single dialysis,</abstract><cop>China</cop><pmid>22954919</pmid><doi>10.3969/j.issn.1672-7347.2012.08.015</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1672-7347 |
| ispartof | Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban, 2012-08, Vol.37 (8), p.844-848 |
| issn | 1672-7347 |
| language | chi |
| recordid | cdi_proquest_miscellaneous_1038591392 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adolescent Adult Aged Aged, 80 and over Anemia - drug therapy Anemia - etiology Female Ferric Compounds - administration & dosage Glucaric Acid Humans Injections, Intravenous Kidney Failure, Chronic - complications Kidney Failure, Chronic - drug therapy Male Middle Aged Oxidative Stress - drug effects Renal Dialysis Sucrose - administration & dosage Young Adult |
| title | Multi-frequency low-dose intravenous iron on oxidative stress in maintenance hemodialysis patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T17%3A35%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Multi-frequency%20low-dose%20intravenous%20iron%20on%20oxidative%20stress%20in%20maintenance%20hemodialysis%20patients&rft.jtitle=Zhong%20nan%20da%20xue%20xue%20bao.%20Journal%20of%20Central%20South%20University.%20Yi%20xue%20ban&rft.au=Yin,%20Li&rft.date=2012-08&rft.volume=37&rft.issue=8&rft.spage=844&rft.epage=848&rft.pages=844-848&rft.issn=1672-7347&rft_id=info:doi/10.3969/j.issn.1672-7347.2012.08.015&rft_dat=%3Cproquest_pubme%3E1038591392%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1038591392&rft_id=info:pmid/22954919&rfr_iscdi=true |