Interaction between sex hormones and WNT/β-catenin signal transduction in endometrial physiology and disease

► During early development, Wnt signalling is essential for Müllerian duct development. ► In physiology, Wnt signalling regulated by sexhormones maintains monthly homeostasis. ► During pregnancy Wnt signalling is essential for proper implantation and placentation. ► Enhanced myometrial Wnt/β-catenin...

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Veröffentlicht in:	Molecular and cellular endocrinology 2012-07, Vol.358 (2), p.176-184
Hauptverfasser:	van der Horst, Paul H., Wang, Yongyi, van der Zee, Marten, Burger, Curt W., Blok, Leen J.
Format:	Artikel
Sprache:	eng
Schlagworte:	adults Animals carcinogenesis Carcinogens Cellular cervix Differentiation Ducts early development Embryo Implantation - physiology Endometrium Endometrium - metabolism Endometrium - physiopathology Estrogen Female Gonadal Steroid Hormones - metabolism Humans Implantation Myometrium Müllerian-duct oviducts Physiology Placentation Pregnancy Progesterone Sex hormones signal transduction Signalling space and time trophoblast Uterine Diseases - metabolism Uterine Diseases - physiopathology vagina Wnt Signaling Pathway Wnt/β-catenin
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