Bionanoparticles of amphiphilic copolymers polyacrylate bearing cholesterol and ascorbate for drug delivery

[Display omitted] ► The core–shell-shaped micelles were formed by the self-assemble of PCholDEGA-block-(PAAA-rad-PBnAAA). ► A bilayer smectic A structure was detected for the polymers having long PCholDEGA-block. ► Strong hydrophobic interaction of PCholDEGA-block led to the high-loading efficiency...

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Veröffentlicht in:	Journal of colloid and interface science 2012-07, Vol.377 (1), p.197-206
Hauptverfasser:	Liu, Yijiang, Wang, Yanzhai, Zhuang, Dequan, Yang, Junjiao, Yang, Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylates - chemistry aqueous solutions Ascorbate Ascorbic Acid - chemistry Bearing Block polymer Chemistry Cholesterol Cholesterol - chemistry Colloidal state and disperse state composite polymers Controlled polymerization Copolymers Differential scanning calorimetry Diffraction Drug delivery Drug Delivery Systems Exact sciences and technology General and physical chemistry hydrophilicity hydrophobicity ibuprofen light scattering micelles Micelles. Thin films nanoparticles Nanoparticles - chemistry Nanostructure Particle Size Physical and chemical studies. Granulometry. Electrokinetic phenomena Polyacrylates Polymers - chemical synthesis Polymers - chemistry Self assembly Surface Properties Surface-Active Agents - chemical synthesis Surface-Active Agents - chemistry temperature thermogravimetry transmission electron microscopy turbidity ultraviolet-visible spectroscopy X-ray diffraction X-rays
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