The Role of Organic Linkers in Directing DNA Self-Assembly and Significantly Stabilizing DNA Duplexes

We show a simple method to control both the stability and the self-assembly behavior of DNA structures. By connecting two adjacent duplexes with small synthetic linkers, factors such as linker rigidity and DNA strand orientation can increase the thermal denaturation temperature of 17 base-pair duple...

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Veröffentlicht in:	Journal of the American Chemical Society 2012-09, Vol.134 (35), p.14382-14389
Hauptverfasser:	Greschner, Andrea A, Toader, Violeta, Sleiman, Hanadi F
Format:	Artikel
Sprache:	eng
Schlagworte:	Dimerization DNA - chemistry Models, Molecular Nucleic Acid Conformation Organic Chemicals - chemistry
Online-Zugang:	Volltext
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