Impact of reactive oxygen species on keratinocyte signaling pathways

Abstract Human epidermal keratinocytes are located on the body surface, which is a specialized location for component cells of human skin tissue. Those cells are always exposed to external stimuli, which constantly generate reactive oxygen species (ROS) in the cells. Regulation of the redox state is...

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Veröffentlicht in:	Journal of dermatological science 2012-10, Vol.68 (1), p.3-8
Hauptverfasser:	Bito, Toshinori, Nishigori, Chikako
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants Antioxidants - pharmacology Dermatitis, Atopic - etiology Dermatitis, Atopic - metabolism Dermatology DNA damage Humans Keratinocytes Keratinocytes - drug effects Keratinocytes - metabolism Keratinocytes - radiation effects Oxidation-Reduction Oxidative Stress - drug effects Oxidative Stress - radiation effects Psoriasis - etiology Psoriasis - metabolism Reactive oxygen species Reactive Oxygen Species - metabolism Signal Transduction - drug effects Signal Transduction - radiation effects Skin Skin Neoplasms - etiology Skin Neoplasms - metabolism STAT3 protein Sunscreening Agents - pharmacology
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