Advanced age is an independent predictor for increased morbidity and mortality after emergent surgery for diverticulitis
Background The objectives of our study were to determine the association between age and postoperative outcomes after emergency surgery for diverticulitis and to identify risk factors for postoperative mortality among elderly patients. Methods All patients from the American College of Surgeons Natio...
Gespeichert in:
| Veröffentlicht in: | Surgery 2012-09, Vol.152 (3), p.465-472 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 472 |
|---|---|
| container_issue | 3 |
| container_start_page | 465 |
| container_title | Surgery |
| container_volume | 152 |
| creator | Lidsky, Michael E., MD Thacker, Julie K. Marosky, MD Lagoo-Deenadayalan, Sandhya A., MD, PhD Scarborough, John E., MD |
| description | Background The objectives of our study were to determine the association between age and postoperative outcomes after emergency surgery for diverticulitis and to identify risk factors for postoperative mortality among elderly patients. Methods All patients from the American College of Surgeons National Surgical Quality Improvement Program 2005–2009 Participant User Files undergoing emergent surgery for diverticulitis were included. Multivariate logistic regression was used to determine the association between age and postoperative morbidity and mortality after adjustment for perioperative variables. A separate regression model was used to determine risk factors for postoperative mortality among elderly patients, with specific postoperative complications being included as potential predictors. Results We included 2,264 patients for analysis, of whom 1,267 (56%) were |
| doi_str_mv | 10.1016/j.surg.2012.06.038 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1037892854</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0039606012003509</els_id><sourcerecordid>1037892854</sourcerecordid><originalsourceid>FETCH-LOGICAL-c441t-d563832a2644b9945ca554f80cd079fb440bff38dfd0116cd2655718eae11b953</originalsourceid><addsrcrecordid>eNp9kk2LFDEQhhtR3NnVP-BB-iJ46bby2R0QYVl0FRY8qOeQTipDxv4Yk-7B-femZ0YFDx7yUfC8VZU3VRQvCNQEiHyzq9MStzUFQmuQNbD2UbEhgtGqYZI8LjYATFUSJFwV1yntAEBx0j4trihVrFUgNsXPW3cwo0VXmi2WIZVmLMPocI95G-dyH9EFO0-x9HmF0UY0KdPDFLvgwnzMglM0m_4U-RljiQPG7SpfG8R4PIldOGCcg10yGNKz4ok3fcLnl_Om-Pbh_de7j9XD5_tPd7cPleWczJUTkrWMGio575TiwhohuG_BOmiU7ziHznvWOu-AEGkdlUI0pEWDhHRKsJvi9TnvPk4_FkyzHkKy2PdmxGlJmgBrWkVbwTNKz6iNU0oRvd7HMJh4zJBeHdc7vT5Ir45rkDo7nkUvL_mXbkD3R_Lb4gy8ugAmWdP7mO0O6S8nmeBNs3JvzxxmNw4Bo0424Po1IaKdtZvC__t494_c9mEMueJ3PGLaTUscs8-a6JQ1-ss6G-toEJpvAhT7BffAteg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1037892854</pqid></control><display><type>article</type><title>Advanced age is an independent predictor for increased morbidity and mortality after emergent surgery for diverticulitis</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Lidsky, Michael E., MD ; Thacker, Julie K. Marosky, MD ; Lagoo-Deenadayalan, Sandhya A., MD, PhD ; Scarborough, John E., MD</creator><creatorcontrib>Lidsky, Michael E., MD ; Thacker, Julie K. Marosky, MD ; Lagoo-Deenadayalan, Sandhya A., MD, PhD ; Scarborough, John E., MD</creatorcontrib><description>Background The objectives of our study were to determine the association between age and postoperative outcomes after emergency surgery for diverticulitis and to identify risk factors for postoperative mortality among elderly patients. Methods All patients from the American College of Surgeons National Surgical Quality Improvement Program 2005–2009 Participant User Files undergoing emergent surgery for diverticulitis were included. Multivariate logistic regression was used to determine the association between age and postoperative morbidity and mortality after adjustment for perioperative variables. A separate regression model was used to determine risk factors for postoperative mortality among elderly patients, with specific postoperative complications being included as potential predictors. Results We included 2,264 patients for analysis, of whom 1,267 (56%) were <65 years old (nonelderly), 648 (28.6%) were 65–79 years old (elderly), and 349 (15.4%) were ≥80 years old (super-elderly). Advanced age was a significant predictor of 30-day postoperative mortality, and to a lesser extent postoperative morbidity. Among those patients ≥65 years old, super-elderly age classification remained a significant predictor of mortality after adjustment for the presence or absence of postoperative complications. Mortality among elderly and super-elderly patients was greatest in the setting of specific complications, such as septic shock, prolonged postoperative mechanical ventilation, and acute renal failure. Conclusion Advanced age is an independent risk factor for death after emergency surgery for diverticulitis, with mortality being greatest among elderly patients who experience certain postoperative complications. Prevention of these complications should form the cornerstone of initiatives designed to lower the mortality associated with emergency surgery in elderly patients.</description><identifier>ISSN: 0039-6060</identifier><identifier>EISSN: 1532-7361</identifier><identifier>DOI: 10.1016/j.surg.2012.06.038</identifier><identifier>PMID: 22938905</identifier><identifier>CODEN: SURGAZ</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Acute Kidney Injury - epidemiology ; Age Factors ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Comorbidity ; Diverticulitis - mortality ; Diverticulitis - surgery ; Epidemiology ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; General aspects ; Humans ; Length of Stay ; Male ; Medical sciences ; Middle Aged ; Multivariate Analysis ; Other diseases. Semiology ; Postoperative Complications - classification ; Postoperative Complications - epidemiology ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Regression Analysis ; Risk Factors ; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus ; Surgery ; Survival Rate ; Treatment Outcome</subject><ispartof>Surgery, 2012-09, Vol.152 (3), p.465-472</ispartof><rights>Mosby, Inc.</rights><rights>2012 Mosby, Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2012 Mosby, Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c441t-d563832a2644b9945ca554f80cd079fb440bff38dfd0116cd2655718eae11b953</citedby><cites>FETCH-LOGICAL-c441t-d563832a2644b9945ca554f80cd079fb440bff38dfd0116cd2655718eae11b953</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0039606012003509$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26354775$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22938905$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lidsky, Michael E., MD</creatorcontrib><creatorcontrib>Thacker, Julie K. Marosky, MD</creatorcontrib><creatorcontrib>Lagoo-Deenadayalan, Sandhya A., MD, PhD</creatorcontrib><creatorcontrib>Scarborough, John E., MD</creatorcontrib><title>Advanced age is an independent predictor for increased morbidity and mortality after emergent surgery for diverticulitis</title><title>Surgery</title><addtitle>Surgery</addtitle><description>Background The objectives of our study were to determine the association between age and postoperative outcomes after emergency surgery for diverticulitis and to identify risk factors for postoperative mortality among elderly patients. Methods All patients from the American College of Surgeons National Surgical Quality Improvement Program 2005–2009 Participant User Files undergoing emergent surgery for diverticulitis were included. Multivariate logistic regression was used to determine the association between age and postoperative morbidity and mortality after adjustment for perioperative variables. A separate regression model was used to determine risk factors for postoperative mortality among elderly patients, with specific postoperative complications being included as potential predictors. Results We included 2,264 patients for analysis, of whom 1,267 (56%) were <65 years old (nonelderly), 648 (28.6%) were 65–79 years old (elderly), and 349 (15.4%) were ≥80 years old (super-elderly). Advanced age was a significant predictor of 30-day postoperative mortality, and to a lesser extent postoperative morbidity. Among those patients ≥65 years old, super-elderly age classification remained a significant predictor of mortality after adjustment for the presence or absence of postoperative complications. Mortality among elderly and super-elderly patients was greatest in the setting of specific complications, such as septic shock, prolonged postoperative mechanical ventilation, and acute renal failure. Conclusion Advanced age is an independent risk factor for death after emergency surgery for diverticulitis, with mortality being greatest among elderly patients who experience certain postoperative complications. Prevention of these complications should form the cornerstone of initiatives designed to lower the mortality associated with emergency surgery in elderly patients.</description><subject>Acute Kidney Injury - epidemiology</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Comorbidity</subject><subject>Diverticulitis - mortality</subject><subject>Diverticulitis - surgery</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>General aspects</subject><subject>Humans</subject><subject>Length of Stay</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Other diseases. Semiology</subject><subject>Postoperative Complications - classification</subject><subject>Postoperative Complications - epidemiology</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Regression Analysis</subject><subject>Risk Factors</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><subject>Surgery</subject><subject>Survival Rate</subject><subject>Treatment Outcome</subject><issn>0039-6060</issn><issn>1532-7361</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kk2LFDEQhhtR3NnVP-BB-iJ46bby2R0QYVl0FRY8qOeQTipDxv4Yk-7B-femZ0YFDx7yUfC8VZU3VRQvCNQEiHyzq9MStzUFQmuQNbD2UbEhgtGqYZI8LjYATFUSJFwV1yntAEBx0j4trihVrFUgNsXPW3cwo0VXmi2WIZVmLMPocI95G-dyH9EFO0-x9HmF0UY0KdPDFLvgwnzMglM0m_4U-RljiQPG7SpfG8R4PIldOGCcg10yGNKz4ok3fcLnl_Om-Pbh_de7j9XD5_tPd7cPleWczJUTkrWMGio575TiwhohuG_BOmiU7ziHznvWOu-AEGkdlUI0pEWDhHRKsJvi9TnvPk4_FkyzHkKy2PdmxGlJmgBrWkVbwTNKz6iNU0oRvd7HMJh4zJBeHdc7vT5Ir45rkDo7nkUvL_mXbkD3R_Lb4gy8ugAmWdP7mO0O6S8nmeBNs3JvzxxmNw4Bo0424Po1IaKdtZvC__t494_c9mEMueJ3PGLaTUscs8-a6JQ1-ss6G-toEJpvAhT7BffAteg</recordid><startdate>20120901</startdate><enddate>20120901</enddate><creator>Lidsky, Michael E., MD</creator><creator>Thacker, Julie K. Marosky, MD</creator><creator>Lagoo-Deenadayalan, Sandhya A., MD, PhD</creator><creator>Scarborough, John E., MD</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120901</creationdate><title>Advanced age is an independent predictor for increased morbidity and mortality after emergent surgery for diverticulitis</title><author>Lidsky, Michael E., MD ; Thacker, Julie K. Marosky, MD ; Lagoo-Deenadayalan, Sandhya A., MD, PhD ; Scarborough, John E., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c441t-d563832a2644b9945ca554f80cd079fb440bff38dfd0116cd2655718eae11b953</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Acute Kidney Injury - epidemiology</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Comorbidity</topic><topic>Diverticulitis - mortality</topic><topic>Diverticulitis - surgery</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>General aspects</topic><topic>Humans</topic><topic>Length of Stay</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Other diseases. Semiology</topic><topic>Postoperative Complications - classification</topic><topic>Postoperative Complications - epidemiology</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Regression Analysis</topic><topic>Risk Factors</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><topic>Surgery</topic><topic>Survival Rate</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lidsky, Michael E., MD</creatorcontrib><creatorcontrib>Thacker, Julie K. Marosky, MD</creatorcontrib><creatorcontrib>Lagoo-Deenadayalan, Sandhya A., MD, PhD</creatorcontrib><creatorcontrib>Scarborough, John E., MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lidsky, Michael E., MD</au><au>Thacker, Julie K. Marosky, MD</au><au>Lagoo-Deenadayalan, Sandhya A., MD, PhD</au><au>Scarborough, John E., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Advanced age is an independent predictor for increased morbidity and mortality after emergent surgery for diverticulitis</atitle><jtitle>Surgery</jtitle><addtitle>Surgery</addtitle><date>2012-09-01</date><risdate>2012</risdate><volume>152</volume><issue>3</issue><spage>465</spage><epage>472</epage><pages>465-472</pages><issn>0039-6060</issn><eissn>1532-7361</eissn><coden>SURGAZ</coden><abstract>Background The objectives of our study were to determine the association between age and postoperative outcomes after emergency surgery for diverticulitis and to identify risk factors for postoperative mortality among elderly patients. Methods All patients from the American College of Surgeons National Surgical Quality Improvement Program 2005–2009 Participant User Files undergoing emergent surgery for diverticulitis were included. Multivariate logistic regression was used to determine the association between age and postoperative morbidity and mortality after adjustment for perioperative variables. A separate regression model was used to determine risk factors for postoperative mortality among elderly patients, with specific postoperative complications being included as potential predictors. Results We included 2,264 patients for analysis, of whom 1,267 (56%) were <65 years old (nonelderly), 648 (28.6%) were 65–79 years old (elderly), and 349 (15.4%) were ≥80 years old (super-elderly). Advanced age was a significant predictor of 30-day postoperative mortality, and to a lesser extent postoperative morbidity. Among those patients ≥65 years old, super-elderly age classification remained a significant predictor of mortality after adjustment for the presence or absence of postoperative complications. Mortality among elderly and super-elderly patients was greatest in the setting of specific complications, such as septic shock, prolonged postoperative mechanical ventilation, and acute renal failure. Conclusion Advanced age is an independent risk factor for death after emergency surgery for diverticulitis, with mortality being greatest among elderly patients who experience certain postoperative complications. Prevention of these complications should form the cornerstone of initiatives designed to lower the mortality associated with emergency surgery in elderly patients.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>22938905</pmid><doi>10.1016/j.surg.2012.06.038</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0039-6060 |
| ispartof | Surgery, 2012-09, Vol.152 (3), p.465-472 |
| issn | 0039-6060 1532-7361 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1037892854 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Acute Kidney Injury - epidemiology Age Factors Aged Aged, 80 and over Biological and medical sciences Comorbidity Diverticulitis - mortality Diverticulitis - surgery Epidemiology Female Gastroenterology. Liver. Pancreas. Abdomen General aspects Humans Length of Stay Male Medical sciences Middle Aged Multivariate Analysis Other diseases. Semiology Postoperative Complications - classification Postoperative Complications - epidemiology Public health. Hygiene Public health. Hygiene-occupational medicine Regression Analysis Risk Factors Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Surgery Survival Rate Treatment Outcome |
| title | Advanced age is an independent predictor for increased morbidity and mortality after emergent surgery for diverticulitis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T03%3A46%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Advanced%20age%20is%20an%20independent%20predictor%20for%20increased%20morbidity%20and%20mortality%20after%20emergent%20surgery%20for%20diverticulitis&rft.jtitle=Surgery&rft.au=Lidsky,%20Michael%20E.,%20MD&rft.date=2012-09-01&rft.volume=152&rft.issue=3&rft.spage=465&rft.epage=472&rft.pages=465-472&rft.issn=0039-6060&rft.eissn=1532-7361&rft.coden=SURGAZ&rft_id=info:doi/10.1016/j.surg.2012.06.038&rft_dat=%3Cproquest_cross%3E1037892854%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1037892854&rft_id=info:pmid/22938905&rft_els_id=1_s2_0_S0039606012003509&rfr_iscdi=true |