Factors affecting mortality in Fournier's gangrene: experience with fifty-two patients
Fournier's gangrene (FG) is a life-threatening infection of the perineal and genital areas. We examined the comorbid diseases, treatments and factors affecting mortality in FG. This retrospective clinical study involved 52 patients who were treated for FG. The demographics, aetiologies, comorbi...
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| Veröffentlicht in: | Singapore medical journal 2012-08, Vol.53 (8), p.537-540 |
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| creator | ERSOZ, Feyzullah SARI, Serkan ARIKAN, Soykan ALTIOK, Melih BEKTAS, Hasan ADAS, Gokhan POYRAZ, Bekir OZCAN, Ozhan |
| description | Fournier's gangrene (FG) is a life-threatening infection of the perineal and genital areas. We examined the comorbid diseases, treatments and factors affecting mortality in FG.
This retrospective clinical study involved 52 patients who were treated for FG. The demographics, aetiologies, comorbid diseases, laboratory and bacteriology findings, treatment methods and length of hospital stay were compared between patients who died and those who survived the infection.
Out of the 52 patients, 12 died and 40 survived. Patients who died and those who survived were similar in terms of their mean age at first presentation (62 vs. 55 years), the mean number of debridements (3.6 vs. 2.9), the mean length of hospital stay (25 vs. 34 days) and gender (p > 0.05 for each). However, the mean leukocyte count was higher in patients who died than in surviving patients (33.6 ± 7.2 vs. 14.3 ± 4.9 cells/mml; p < 0.05). The most common aetiology in both groups was perianal abscess. Deviating colostomy was performed in 13 patients. Of the patients who died, nine had haemodialysis-dependent chronic renal failure and type II diabetes mellitus (DM), while one had type II DM and hypertension.
Haemodialysis-dependent chronic renal failure and a high leukocyte count at first presentation were found to be the factors affecting mortality in FG patients. |
| format | Article |
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This retrospective clinical study involved 52 patients who were treated for FG. The demographics, aetiologies, comorbid diseases, laboratory and bacteriology findings, treatment methods and length of hospital stay were compared between patients who died and those who survived the infection.
Out of the 52 patients, 12 died and 40 survived. Patients who died and those who survived were similar in terms of their mean age at first presentation (62 vs. 55 years), the mean number of debridements (3.6 vs. 2.9), the mean length of hospital stay (25 vs. 34 days) and gender (p > 0.05 for each). However, the mean leukocyte count was higher in patients who died than in surviving patients (33.6 ± 7.2 vs. 14.3 ± 4.9 cells/mml; p < 0.05). The most common aetiology in both groups was perianal abscess. Deviating colostomy was performed in 13 patients. Of the patients who died, nine had haemodialysis-dependent chronic renal failure and type II diabetes mellitus (DM), while one had type II DM and hypertension.
Haemodialysis-dependent chronic renal failure and a high leukocyte count at first presentation were found to be the factors affecting mortality in FG patients.</description><identifier>ISSN: 0037-5675</identifier><identifier>PMID: 22941132</identifier><identifier>CODEN: SIMJA3</identifier><language>eng</language><publisher>Singapore: Singapore Medical Association</publisher><subject>Adult ; Aged ; Anti-Bacterial Agents - therapeutic use ; Bacterial diseases ; Bacterial diseases of the nervous system. Bacterial myositis ; Biological and medical sciences ; Comorbidity ; Debridement - methods ; Female ; Fournier Gangrene - complications ; Fournier Gangrene - mortality ; Fournier Gangrene - therapy ; General aspects ; Human bacterial diseases ; Humans ; Infectious diseases ; Kidney Failure, Chronic - etiology ; Length of Stay ; Leukocyte Count ; Male ; Medical sciences ; Middle Aged ; Nephrology. Urinary tract diseases ; Nephropathies. Renovascular diseases. Renal failure ; Renal failure ; Retrospective Studies ; Risk Factors ; Survival Rate</subject><ispartof>Singapore medical journal, 2012-08, Vol.53 (8), p.537-540</ispartof><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26450811$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22941132$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ERSOZ, Feyzullah</creatorcontrib><creatorcontrib>SARI, Serkan</creatorcontrib><creatorcontrib>ARIKAN, Soykan</creatorcontrib><creatorcontrib>ALTIOK, Melih</creatorcontrib><creatorcontrib>BEKTAS, Hasan</creatorcontrib><creatorcontrib>ADAS, Gokhan</creatorcontrib><creatorcontrib>POYRAZ, Bekir</creatorcontrib><creatorcontrib>OZCAN, Ozhan</creatorcontrib><title>Factors affecting mortality in Fournier's gangrene: experience with fifty-two patients</title><title>Singapore medical journal</title><addtitle>Singapore Med J</addtitle><description>Fournier's gangrene (FG) is a life-threatening infection of the perineal and genital areas. We examined the comorbid diseases, treatments and factors affecting mortality in FG.
This retrospective clinical study involved 52 patients who were treated for FG. The demographics, aetiologies, comorbid diseases, laboratory and bacteriology findings, treatment methods and length of hospital stay were compared between patients who died and those who survived the infection.
Out of the 52 patients, 12 died and 40 survived. Patients who died and those who survived were similar in terms of their mean age at first presentation (62 vs. 55 years), the mean number of debridements (3.6 vs. 2.9), the mean length of hospital stay (25 vs. 34 days) and gender (p > 0.05 for each). However, the mean leukocyte count was higher in patients who died than in surviving patients (33.6 ± 7.2 vs. 14.3 ± 4.9 cells/mml; p < 0.05). The most common aetiology in both groups was perianal abscess. Deviating colostomy was performed in 13 patients. Of the patients who died, nine had haemodialysis-dependent chronic renal failure and type II diabetes mellitus (DM), while one had type II DM and hypertension.
Haemodialysis-dependent chronic renal failure and a high leukocyte count at first presentation were found to be the factors affecting mortality in FG patients.</description><subject>Adult</subject><subject>Aged</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Bacterial diseases</subject><subject>Bacterial diseases of the nervous system. Bacterial myositis</subject><subject>Biological and medical sciences</subject><subject>Comorbidity</subject><subject>Debridement - methods</subject><subject>Female</subject><subject>Fournier Gangrene - complications</subject><subject>Fournier Gangrene - mortality</subject><subject>Fournier Gangrene - therapy</subject><subject>General aspects</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Kidney Failure, Chronic - etiology</subject><subject>Length of Stay</subject><subject>Leukocyte Count</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Nephropathies. Renovascular diseases. Renal failure</subject><subject>Renal failure</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Survival Rate</subject><issn>0037-5675</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0MFLwzAYBfAcFDen_4LkInopJGnatN5kOBUGXtRr-Zp8mZE2rUnK3H9vwYmnB48f7_BOyJKxXGVFqYoFOY_xkzGhWFWdkYUQteQ8F0vyvgGdhhApWIs6Ob-j_RASdC4dqPN0M0zBOww3ke7A7wJ6vKP4PWJw6DXSvUsf1DqbDlnaD3SENPcpXpBTC13Ey2OuyNvm4XX9lG1fHp_X99tsFJKnTLW1ZdLYkllkqlRQtKYQvORCF2CxqlAwY1XLNBrO0UqUxiBowY3hOod8RW5_d8cwfE0YU9O7qLHrwOMwxYbPD1S1KGs506sjndoeTTMG10M4NH9fzOD6CCBq6GwAr138d6UsWDXLH09paL0</recordid><startdate>20120801</startdate><enddate>20120801</enddate><creator>ERSOZ, Feyzullah</creator><creator>SARI, Serkan</creator><creator>ARIKAN, Soykan</creator><creator>ALTIOK, Melih</creator><creator>BEKTAS, Hasan</creator><creator>ADAS, Gokhan</creator><creator>POYRAZ, Bekir</creator><creator>OZCAN, Ozhan</creator><general>Singapore Medical Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20120801</creationdate><title>Factors affecting mortality in Fournier's gangrene: experience with fifty-two patients</title><author>ERSOZ, Feyzullah ; SARI, Serkan ; ARIKAN, Soykan ; ALTIOK, Melih ; BEKTAS, Hasan ; ADAS, Gokhan ; POYRAZ, Bekir ; OZCAN, Ozhan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p241t-7b9f04df60fe0767a5bd521612c5afe88e20df7b0ced11ef4e4ddeac21dd1c3a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Bacterial diseases</topic><topic>Bacterial diseases of the nervous system. Bacterial myositis</topic><topic>Biological and medical sciences</topic><topic>Comorbidity</topic><topic>Debridement - methods</topic><topic>Female</topic><topic>Fournier Gangrene - complications</topic><topic>Fournier Gangrene - mortality</topic><topic>Fournier Gangrene - therapy</topic><topic>General aspects</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Kidney Failure, Chronic - etiology</topic><topic>Length of Stay</topic><topic>Leukocyte Count</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Nephropathies. Renovascular diseases. Renal failure</topic><topic>Renal failure</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ERSOZ, Feyzullah</creatorcontrib><creatorcontrib>SARI, Serkan</creatorcontrib><creatorcontrib>ARIKAN, Soykan</creatorcontrib><creatorcontrib>ALTIOK, Melih</creatorcontrib><creatorcontrib>BEKTAS, Hasan</creatorcontrib><creatorcontrib>ADAS, Gokhan</creatorcontrib><creatorcontrib>POYRAZ, Bekir</creatorcontrib><creatorcontrib>OZCAN, Ozhan</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Singapore medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ERSOZ, Feyzullah</au><au>SARI, Serkan</au><au>ARIKAN, Soykan</au><au>ALTIOK, Melih</au><au>BEKTAS, Hasan</au><au>ADAS, Gokhan</au><au>POYRAZ, Bekir</au><au>OZCAN, Ozhan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Factors affecting mortality in Fournier's gangrene: experience with fifty-two patients</atitle><jtitle>Singapore medical journal</jtitle><addtitle>Singapore Med J</addtitle><date>2012-08-01</date><risdate>2012</risdate><volume>53</volume><issue>8</issue><spage>537</spage><epage>540</epage><pages>537-540</pages><issn>0037-5675</issn><coden>SIMJA3</coden><abstract>Fournier's gangrene (FG) is a life-threatening infection of the perineal and genital areas. We examined the comorbid diseases, treatments and factors affecting mortality in FG.
This retrospective clinical study involved 52 patients who were treated for FG. The demographics, aetiologies, comorbid diseases, laboratory and bacteriology findings, treatment methods and length of hospital stay were compared between patients who died and those who survived the infection.
Out of the 52 patients, 12 died and 40 survived. Patients who died and those who survived were similar in terms of their mean age at first presentation (62 vs. 55 years), the mean number of debridements (3.6 vs. 2.9), the mean length of hospital stay (25 vs. 34 days) and gender (p > 0.05 for each). However, the mean leukocyte count was higher in patients who died than in surviving patients (33.6 ± 7.2 vs. 14.3 ± 4.9 cells/mml; p < 0.05). The most common aetiology in both groups was perianal abscess. Deviating colostomy was performed in 13 patients. Of the patients who died, nine had haemodialysis-dependent chronic renal failure and type II diabetes mellitus (DM), while one had type II DM and hypertension.
Haemodialysis-dependent chronic renal failure and a high leukocyte count at first presentation were found to be the factors affecting mortality in FG patients.</abstract><cop>Singapore</cop><pub>Singapore Medical Association</pub><pmid>22941132</pmid><tpages>4</tpages></addata></record> |
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| subjects | Adult Aged Anti-Bacterial Agents - therapeutic use Bacterial diseases Bacterial diseases of the nervous system. Bacterial myositis Biological and medical sciences Comorbidity Debridement - methods Female Fournier Gangrene - complications Fournier Gangrene - mortality Fournier Gangrene - therapy General aspects Human bacterial diseases Humans Infectious diseases Kidney Failure, Chronic - etiology Length of Stay Leukocyte Count Male Medical sciences Middle Aged Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Renal failure Retrospective Studies Risk Factors Survival Rate |
| title | Factors affecting mortality in Fournier's gangrene: experience with fifty-two patients |
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