Immune responses in dogs with cutaneous adverse food reactions
Adverse food reactions (AFR) in dogs are reactions due to apparently harmless food antigens, with an unknown aetiology, i.e. immunopathogenesis. Despite the entry of food allergens via the intestinal tract, in the majority of dogs with AFR, clinical symptoms are only associated with the skin (CAFR)....
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Veröffentlicht in: | The Veterinary quarterly 2012-06, Vol.32 (2), p.87-98 |
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description | Adverse food reactions (AFR) in dogs are reactions due to apparently harmless food antigens, with an unknown aetiology, i.e. immunopathogenesis. Despite the entry of food allergens via the intestinal tract, in the majority of dogs with AFR, clinical symptoms are only associated with the skin (CAFR). In the present review, factors are presented of relevance in triggering the differentiation of naive T cells into effector T cell types and the role of these T cell types in allergy. More specifically, the allergic immune responses in intestine and skin are discussed in this article as well as the potential pathways, e.g. homing of antigen presenting cells or allergen-induced T cells to the skin, of induction of cutaneous symptoms. |
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subjects | adverse food reaction Allergens - immunology allergy Animals dog Dog Diseases - immunology Dogs Food Hypersensitivity - immunology Food Hypersensitivity - veterinary IgE intestine Intestines - immunology skin Skin - immunology T-Lymphocytes - immunology |
title | Immune responses in dogs with cutaneous adverse food reactions |
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