Immune responses in dogs with cutaneous adverse food reactions

Adverse food reactions (AFR) in dogs are reactions due to apparently harmless food antigens, with an unknown aetiology, i.e. immunopathogenesis. Despite the entry of food allergens via the intestinal tract, in the majority of dogs with AFR, clinical symptoms are only associated with the skin (CAFR)....

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Veröffentlicht in:The Veterinary quarterly 2012-06, Vol.32 (2), p.87-98
Hauptverfasser: Veenhof, E.Z., Knol, E.F., Willemse, T., Rutten, V.P.M.G.
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container_issue 2
container_start_page 87
container_title The Veterinary quarterly
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creator Veenhof, E.Z.
Knol, E.F.
Willemse, T.
Rutten, V.P.M.G.
description Adverse food reactions (AFR) in dogs are reactions due to apparently harmless food antigens, with an unknown aetiology, i.e. immunopathogenesis. Despite the entry of food allergens via the intestinal tract, in the majority of dogs with AFR, clinical symptoms are only associated with the skin (CAFR). In the present review, factors are presented of relevance in triggering the differentiation of naive T cells into effector T cell types and the role of these T cell types in allergy. More specifically, the allergic immune responses in intestine and skin are discussed in this article as well as the potential pathways, e.g. homing of antigen presenting cells or allergen-induced T cells to the skin, of induction of cutaneous symptoms.
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subjects adverse food reaction
Allergens - immunology
allergy
Animals
dog
Dog Diseases - immunology
Dogs
Food Hypersensitivity - immunology
Food Hypersensitivity - veterinary
IgE
intestine
Intestines - immunology
skin
Skin - immunology
T-Lymphocytes - immunology
title Immune responses in dogs with cutaneous adverse food reactions
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