Allergen specificity of IgG(4)-expressing B cells in patients with grass pollen allergy undergoing immunotherapy

Serum IgG(4) responses to allergen immunotherapy are well documented as blocking allergen binding to receptor-bound IgE on antigen-presenting cells and effector cells, but the molecular characteristics of treatment-induced IgG(4), particularly in relation to expressed antibody, are poorly defined. W...

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Veröffentlicht in:Journal of allergy and clinical immunology 2012-09, Vol.130 (3), p.663-670.e3
Hauptverfasser: James, Louisa K, Bowen, Holly, Calvert, Rosaleen A, Dodev, Tihomir S, Shamji, Mohamed H, Beavil, Andrew J, McDonnell, James M, Durham, Stephen R, Gould, Hannah J
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Sprache:eng
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