The results of treatment of primary brain tumors in children
During the period of 2009-2011 in UCH in Belgrade, we treated 22 patients with brain tumors. Treatment included the diagnosis and therapy that included surgery and postoperative neuroradiological follow-up of all patients regardless of whether radiotherapy was conducted with or without chemotherapy....
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Veröffentlicht in: | Acta chirurgica Iugoslavica 2012, Vol.59 (1), p.45-48 |
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creator | Mrdak, Milan Mihajlović, Miljan Nikolić, Igor Repa, Nikola Jovanović, Vladimir Sćepanović, Vuk Janićijević, Aleksandar Bogdanović, Ivan Nestorović, Branislav Tasić, Goran |
description | During the period of 2009-2011 in UCH in Belgrade, we treated 22 patients with brain tumors. Treatment included the diagnosis and therapy that included surgery and postoperative neuroradiological follow-up of all patients regardless of whether radiotherapy was conducted with or without chemotherapy. The most frequent were low grade astrocytomas and medulloblastomas. Patients with supratentorial localization of tumor had significantly smaller neurological sequelae compared with patients with infratentorial as well as patients diagnosed with low grade astrocytomas of any localization. From 10 patients with supratentorial localization, 7 of them had no neurological deficit, while from 11 patients with infratentorial localization, 3 of them were Without deficit. Patients with histological diagnosis of low grade astrocytoma of any localization had less neurological deficits compared with other tumors. From 7 low grade astrocytoma in 5 of them there was no neurological deficit, while only in one patient residual tumor was verified. In 7 patients the rest of the tumor was diagnosed, while in 14 patients no residual tumors was diagnosed during follow-up based on the MRI diagnosis. Surgery, postoperative radiotherapy and chemotherapy in some cases represent an effective therapeutic approach in the treatment of brain tumors in children. |
doi_str_mv | 10.2298/ACI1201045M |
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Treatment included the diagnosis and therapy that included surgery and postoperative neuroradiological follow-up of all patients regardless of whether radiotherapy was conducted with or without chemotherapy. The most frequent were low grade astrocytomas and medulloblastomas. Patients with supratentorial localization of tumor had significantly smaller neurological sequelae compared with patients with infratentorial as well as patients diagnosed with low grade astrocytomas of any localization. From 10 patients with supratentorial localization, 7 of them had no neurological deficit, while from 11 patients with infratentorial localization, 3 of them were Without deficit. Patients with histological diagnosis of low grade astrocytoma of any localization had less neurological deficits compared with other tumors. From 7 low grade astrocytoma in 5 of them there was no neurological deficit, while only in one patient residual tumor was verified. In 7 patients the rest of the tumor was diagnosed, while in 14 patients no residual tumors was diagnosed during follow-up based on the MRI diagnosis. 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Treatment included the diagnosis and therapy that included surgery and postoperative neuroradiological follow-up of all patients regardless of whether radiotherapy was conducted with or without chemotherapy. The most frequent were low grade astrocytomas and medulloblastomas. Patients with supratentorial localization of tumor had significantly smaller neurological sequelae compared with patients with infratentorial as well as patients diagnosed with low grade astrocytomas of any localization. From 10 patients with supratentorial localization, 7 of them had no neurological deficit, while from 11 patients with infratentorial localization, 3 of them were Without deficit. Patients with histological diagnosis of low grade astrocytoma of any localization had less neurological deficits compared with other tumors. From 7 low grade astrocytoma in 5 of them there was no neurological deficit, while only in one patient residual tumor was verified. In 7 patients the rest of the tumor was diagnosed, while in 14 patients no residual tumors was diagnosed during follow-up based on the MRI diagnosis. Surgery, postoperative radiotherapy and chemotherapy in some cases represent an effective therapeutic approach in the treatment of brain tumors in children.</description><subject>Adolescent</subject><subject>Astrocytoma - diagnosis</subject><subject>Astrocytoma - surgery</subject><subject>Brain Neoplasms - diagnosis</subject><subject>Brain Neoplasms - surgery</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Combined Modality Therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Male</subject><subject>Medulloblastoma - diagnosis</subject><subject>Medulloblastoma - surgery</subject><issn>0354-950X</issn><issn>2406-0887</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkE1Lw0AQhhdRbK2evEuOgkRnZzfZDXgpwY9CxUsFb2F3O6GRfNTd5OC_b0qreBhmBp55YR7GrjncI2b6YZ4vOAIHmbydsClKSGPQWp2yKYhExlkCnxN2EcIXQIrIxTmbjHcoBeCUPa42FHkKQ92HqCuj3pPpG2r7_bL1VWP8T2S9qdqoH5rOh2ic3Kaq157aS3ZWmjrQ1bHP2Mfz0yp_jZfvL4t8vowdz7ImFlYmJhOZFdwBCL4vZzBVqVQ8MQIs2JISLKXWaBShXkslnEkt10ajEjN2e8jd-u57oNAXTRUc1bVpqRtCwUGkWgMoPqJ3B9T5LgRPZXF8YoSKva7in66RvjkGD7ah9R_760fsANRSYv4</recordid><startdate>2012</startdate><enddate>2012</enddate><creator>Mrdak, Milan</creator><creator>Mihajlović, Miljan</creator><creator>Nikolić, Igor</creator><creator>Repa, Nikola</creator><creator>Jovanović, Vladimir</creator><creator>Sćepanović, Vuk</creator><creator>Janićijević, Aleksandar</creator><creator>Bogdanović, Ivan</creator><creator>Nestorović, Branislav</creator><creator>Tasić, Goran</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-8665-8230</orcidid></search><sort><creationdate>2012</creationdate><title>The results of treatment of primary brain tumors in children</title><author>Mrdak, Milan ; Mihajlović, Miljan ; Nikolić, Igor ; Repa, Nikola ; Jovanović, Vladimir ; Sćepanović, Vuk ; Janićijević, Aleksandar ; Bogdanović, Ivan ; Nestorović, Branislav ; Tasić, Goran</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c199m-3b45a939b31c00310031ca26764715a30b0bfe52f4882a7e28d473ca6b18a8273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adolescent</topic><topic>Astrocytoma - diagnosis</topic><topic>Astrocytoma - surgery</topic><topic>Brain Neoplasms - diagnosis</topic><topic>Brain Neoplasms - surgery</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Combined Modality Therapy</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Male</topic><topic>Medulloblastoma - diagnosis</topic><topic>Medulloblastoma - surgery</topic><toplevel>online_resources</toplevel><creatorcontrib>Mrdak, Milan</creatorcontrib><creatorcontrib>Mihajlović, Miljan</creatorcontrib><creatorcontrib>Nikolić, Igor</creatorcontrib><creatorcontrib>Repa, Nikola</creatorcontrib><creatorcontrib>Jovanović, Vladimir</creatorcontrib><creatorcontrib>Sćepanović, Vuk</creatorcontrib><creatorcontrib>Janićijević, Aleksandar</creatorcontrib><creatorcontrib>Bogdanović, Ivan</creatorcontrib><creatorcontrib>Nestorović, Branislav</creatorcontrib><creatorcontrib>Tasić, Goran</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta chirurgica Iugoslavica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mrdak, Milan</au><au>Mihajlović, Miljan</au><au>Nikolić, Igor</au><au>Repa, Nikola</au><au>Jovanović, Vladimir</au><au>Sćepanović, Vuk</au><au>Janićijević, Aleksandar</au><au>Bogdanović, Ivan</au><au>Nestorović, Branislav</au><au>Tasić, Goran</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The results of treatment of primary brain tumors in children</atitle><jtitle>Acta chirurgica Iugoslavica</jtitle><addtitle>Acta Chir Iugosl</addtitle><date>2012</date><risdate>2012</risdate><volume>59</volume><issue>1</issue><spage>45</spage><epage>48</epage><pages>45-48</pages><issn>0354-950X</issn><eissn>2406-0887</eissn><abstract>During the period of 2009-2011 in UCH in Belgrade, we treated 22 patients with brain tumors. Treatment included the diagnosis and therapy that included surgery and postoperative neuroradiological follow-up of all patients regardless of whether radiotherapy was conducted with or without chemotherapy. The most frequent were low grade astrocytomas and medulloblastomas. Patients with supratentorial localization of tumor had significantly smaller neurological sequelae compared with patients with infratentorial as well as patients diagnosed with low grade astrocytomas of any localization. From 10 patients with supratentorial localization, 7 of them had no neurological deficit, while from 11 patients with infratentorial localization, 3 of them were Without deficit. Patients with histological diagnosis of low grade astrocytoma of any localization had less neurological deficits compared with other tumors. From 7 low grade astrocytoma in 5 of them there was no neurological deficit, while only in one patient residual tumor was verified. In 7 patients the rest of the tumor was diagnosed, while in 14 patients no residual tumors was diagnosed during follow-up based on the MRI diagnosis. Surgery, postoperative radiotherapy and chemotherapy in some cases represent an effective therapeutic approach in the treatment of brain tumors in children.</abstract><cop>Serbia</cop><pmid>22924302</pmid><doi>10.2298/ACI1201045M</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0001-8665-8230</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Astrocytoma - diagnosis Astrocytoma - surgery Brain Neoplasms - diagnosis Brain Neoplasms - surgery Child Child, Preschool Combined Modality Therapy Female Humans Infant Male Medulloblastoma - diagnosis Medulloblastoma - surgery |
title | The results of treatment of primary brain tumors in children |
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