Hypothalamic transcript profiling in hypothermia using SuperSAGE

Abstract Understanding of molecular mechanisms underlying hypothermia is of primary importance in devising strategies to diagnose hypothermia. We investigated the hypothalamic transriptome in hypothermia. For transcriptomic analyses, SuperSAGE, an improved method of serial analysis of gene expressio...

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Veröffentlicht in:	Journal of forensic and legal medicine 2012-10, Vol.19 (7), p.396-401
Hauptverfasser:	Takamiya, Masataka, MD, PhD, Nakayashiki, Nori, PhD, Dewa, Koji, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers Calmodulin-Binding Proteins - genetics Calmodulin-Binding Proteins - metabolism Chromosomal Proteins, Non-Histone - genetics Chromosomal Proteins, Non-Histone - metabolism Dopamine Plasma Membrane Transport Proteins - genetics Dopamine Plasma Membrane Transport Proteins - metabolism Expressed Sequence Tags Fever Forensic Genetics Forensic Pathology Gene expression Gene Expression Profiling Genetic testing HSC70 Heat-Shock Proteins - genetics HSC70 Heat-Shock Proteins - metabolism Hypothalamus Hypothalamus - metabolism Hypothermia Hypothermia - diagnosis Male Medical diagnosis Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Oligonucleotide Array Sequence Analysis - methods Pathology Polymerase Chain Reaction Quantitative PCR Rats Rats, Wistar RNA, Messenger - metabolism SuperSAGE Transcriptome Tryptophan Hydroxylase - genetics Tryptophan Hydroxylase - metabolism Tyrosine 3-Monooxygenase - genetics Tyrosine 3-Monooxygenase - metabolism
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