Prenatal exposure to valproic acid increases the neural progenitor cell pool and induces macrocephaly in rat brain via a mechanism involving the GSK-3β/β-catenin pathway

Autism is a spectrum of neurodevelopmental disorders characterized by social isolation and lack of interaction. Anatomically, autism patients often show macrocephaly and high neuronal density. To investigate the mechanism underlying the higher neuronal populations seen in ASD, we subcutaneously inje...

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Veröffentlicht in:Neuropharmacology 2012-11, Vol.63 (6), p.1028-1041
Hauptverfasser: Go, Hyo Sang, Kim, Ki Chan, Choi, Chang Soon, Jeon, Se Jin, Kwon, Kyung Ja, Han, Seol-Heui, Lee, Jongmin, Cheong, Jae Hoon, Ryu, Jong Hoon, Kim, Chong-Hyun, Ko, Kwang Ho, Shin, Chan Young
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Sprache:eng
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