Whole-Brain Mapping of Direct Inputs to Midbrain Dopamine Neurons

Recent studies indicate that dopamine neurons in the ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) convey distinct signals. To explore this difference, we comprehensively identified each area's monosynaptic inputs using the rabies virus. We show that dopamine neurons in...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2012-06, Vol.74 (5), p.858-873
Hauptverfasser:	Watabe-Uchida, Mitsuko, Zhu, Lisa, Ogawa, Sachie K., Vamanrao, Archana, Uchida, Naoshige
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autonomic nervous system Brain Brain - cytology Brain - physiology Brain Mapping Calbindins Cell Count Dopamine Dopamine Plasma Membrane Transport Proteins - genetics Dopamine Plasma Membrane Transport Proteins - metabolism Dopaminergic Neurons - physiology gamma-Aminobutyric Acid - metabolism Gene expression Luminescent Proteins - genetics Luminescent Proteins - metabolism Mice Mice, Inbred C57BL Models, Biological Neural Pathways - physiology Neurons Parkinson's disease Rabies virus Rabies virus - physiology S100 Calcium Binding Protein G - metabolism Studies Substantia Nigra - cytology Transduction, Genetic Tyrosine 3-Monooxygenase - metabolism Ventral Tegmental Area - cytology
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