Is adoptive T-cell therapy for solid tumors coming of age?

Among the novel biological therapeutics that will increase our ability to cure human cancer in years to come, adoptive cellular therapy is one of the most promising approaches. Although this is a complex and challenging field, there have been major advances in basic and translational research result...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2012-08, Vol.47 (8), p.1013-1019
Hauptverfasser:	Pedrazzoli, P, Comoli, P, Montagna, D, Demirer, T, Bregni, M
Format:	Artikel
Sprache:	eng
Schlagworte:	692/699/67 692/700/565/251 Adoptive Transfer - methods Age Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antigen (tumor-associated) Antigens Biological and medical sciences Bone marrow Bone marrow transplantation Bone marrow, stem cells transplantation. Graft versus host reaction Cancer Care and treatment Cell Biology Cell therapy Cellular therapy Clinical trials Cytotoxicity Epstein-Barr Virus Infections - genetics Epstein-Barr Virus Infections - immunology Epstein-Barr Virus Infections - therapy Health aspects Hematology Herpesvirus 4, Human - immunology Human performance Humans Immunity, Cellular Internal Medicine Lymphocytes Lymphocytes T Malignancy Medical sciences Medicine Medicine & Public Health Melanoma Melanoma - genetics Melanoma - immunology Melanoma - therapy Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Patients Physiological aspects Public Health Receptors, Antigen, T-Cell - genetics Receptors, Antigen, T-Cell - immunology review Solid tumors Stem cell transplantation Stem Cells T cells T-cell receptor T-Lymphocytes - immunology Therapy Toxicity Transduction, Genetic - methods Transfusions. Complications. Transfusion reactions. Cell and gene therapy Translation Tumor cells Tumor Escape - genetics Tumor Escape - immunology Tumor-infiltrating lymphocytes Tumors Viruses
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