Clinical significance of CD81 expression by clonal plasma cells in high-risk smoldering and symptomatic multiple myeloma patients

The presence of CD19 in myelomatous plasma cells (MM-PCs) correlates with adverse prognosis in multiple myeloma (MM). Although CD19 expression is upregulated by CD81, this marker has been poorly investigated and its prognostic value in MM remains unknown. We have analyzed CD81 expression by multipar...

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Veröffentlicht in:	Leukemia 2012-08, Vol.26 (8), p.1862-1869
Hauptverfasser:	Paiva, B, Gutiérrez, N-C, Chen, X, Vídriales, M-B, Montalbán, M-Á, Rosiñol, L, Oriol, A, Martínez-López, J, Mateos, M-V, López-Corral, L, Díaz-Rodríguez, E, Pérez, J-J, Fernández-Redondo, E, de Arriba, F, Palomera, L, Bengoechea, E, Terol, M-J, de Paz, R, Martin, A, Hernández, J, Orfao, A, Lahuerta, J-J, Bladé, J, Pandiella, A, Miguel, J-F San
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/2322 631/67/68 692/699/67/1990/804 692/700/1518 Aged Aged, 80 and over Biological and medical sciences Blood plasma Cancer Research CD19 antigen CD81 antigen Clinical significance Critical Care Medicine Development and progression Diagnosis Flow cytometry Gene expression Gene Expression Regulation, Neoplastic Genetic aspects Hematologic and hematopoietic diseases Hematology Humans Immunodeficiencies. Immunoglobulinopathies Immunoglobulinopathies Immunoglobulins Immunopathology Immunophenotyping Intensive Internal Medicine Leukemia Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Markers Medical prognosis Medical sciences Medicine Medicine & Public Health Middle Aged Multiple myeloma Multiple Myeloma - genetics Multiple Myeloma - metabolism Multiple Myeloma - mortality Oncology original-article Pathogenesis Patients Physiological aspects Plasma Plasma cells Plasma Cells - metabolism Prognosis Smoldering Survival Analysis Tetraspanin 28 - genetics Tetraspanin 28 - metabolism Transplants & implants Working groups
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