Intensification of GVHD prophylaxis with low-dose ATG-F before allogeneic PBSC transplantation from HLA-identical siblings in adult patients with hematological malignancies: results from a retrospective analysis

Several studies have shown that chronic GVHD (cGVHD) is more frequent in patients receiving transplants from PBSC than in those receiving BM. In the setting of PBSC-unrelated transplants, the addition of anti-T-cell globulin (ATG) has shown a significant decrease in incidence/severity of cGVHD, with...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2012-08, Vol.47 (8), p.1105-1111
Hauptverfasser:	Bonifazi, F, Bandini, G, Arpinati, M, Tolomelli, G, Stanzani, M, Motta, M R, Rizzi, S, Giudice, V, Dan, E, Massari, E, Tazzari, P, Bontadini, A, Pagliaro, P, Baccarani, M
Format:	Artikel
Sprache:	eng
Schlagworte:	692/699/249/1529 692/699/67/1990 692/700/459/1748 692/700/565/545/576/1955 Acute Disease Adolescent Adult Aged Amplification Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antilymphocyte Serum - administration & dosage Biological and medical sciences Blood diseases Bone marrow Bone marrow transplantation Bone marrow, stem cells transplantation. Graft versus host reaction Care and treatment Cell Biology Chronic Disease Chronic infection Data processing Disease prevention Female Globulins Graft vs Host Disease - etiology Graft vs Host Disease - prevention & control Graft-versus-host reaction Hematologic Neoplasms - therapy Hematology Histocompatibility antigen HLA Histocompatibility Testing Humans Immunosuppressive Agents - administration & dosage Internal Medicine Lymphocytes T Male Malignancy Medical sciences Medicine Medicine & Public Health Middle Aged original-article Peripheral Blood Stem Cell Transplantation Prophylaxis Public Health Retrospective Studies Siblings Stem cell transplantation Stem Cells Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Transplantation, Homologous Transplants Transplants & implants
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