Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis

Jer-Yuarn Wu, Fuu-Jen Tsai, Yuan-Tsong Chen and colleagues report a genome-wide association study of Kawasaki disease. They show that common variants near BLK and CD40 influence susceptibility to this acute childhood vasculitis. To find new candidate loci predisposing individuals to Kawasaki disease...

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Veröffentlicht in:	Nature genetics 2012-05, Vol.44 (5), p.522-525
Hauptverfasser:	Lee, Yi-Ching, Kuo, Ho-Chang, Chang, Jeng-Sheng, Chang, Luan-Yin, Huang, Li-Min, Chen, Ming-Ren, Liang, Chi-Di, Chi, Hsin, Huang, Fu-Yuan, Lee, Meng-Luen, Huang, Yhu-Chering, Hwang, Betau, Chiu, Nan-Chang, Hwang, Kao-Pin, Lee, Pi-Chang, Chang, Li-Ching, Liu, Yi-Min, Chen, Ying-Ju, Chen, Chien-Hsiun, Alliance, Taiwan Pediatric ID, Chen, Yuan-Tsong, Tsai, Fuu-Jen, Wu, Jer-Yuarn
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/205/2138 631/208/2489/144 Agriculture Animal Genetics and Genomics Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Case-Control Studies Fundamental and applied biological sciences. Psychology Gene Function Genetic Loci Genetic Markers Genetic Predisposition to Disease Genetics of eukaryotes. Biological and molecular evolution Genome-Wide Association Study Human Genetics Humans letter Medical sciences Mucocutaneous Lymph Node Syndrome - genetics Polymorphism, Single Nucleotide - genetics Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Taiwan
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