The PSAa/lo Prostate Cancer Cell Population Harbors Self-Renewing Long-Term Tumor-Propagating Cells that Resist Castration

Prostate cancer (PCa) is heterogeneous and contains both differentiated and undifferentiated tumor cells, but the relative functional contribution of these two cell populations remains unclear. Here we report distinct molecular, cellular, and tumor-propagating properties of PCa cells that express hi...

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Veröffentlicht in:Cell stem cell 2012-05, Vol.10 (5), p.556-569
Hauptverfasser: Qin, Jichao, Liu, Xin, Laffin, Brian, Chen, Xin, Choy, Grace, Jeter, Collene R, Calhoun-Davis, Tammy, Li, Hangwen, Palapattu, Ganesh S, Pang, Shen, Lin, Kevin, Huang, Jiaoti, Ivanov, Ivan, Li, Wei, Suraneni, Mahipal V, Tang, Dean G
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Sprache:eng
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