Immunomodulatory Properties of the Protein Fraction from Phorphyra columbina

The phycobiliproteins from Rhodophyta, R-phycoerythrin (R-PE) and C-phycocyanin (C-PC), have been shown to exert immunomodulatory effects. This study evaluated the effects of a Phorphyra columbina protein fraction (PF) and R-PE and C-PC on rat primary splenocytes, macrophages, and T-lymphocytes in v...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2012-08, Vol.60 (33), p.8146-8154
Hauptverfasser:	Cian, Raúl E, López-Posadas, Rocío, Drago, Silvina R, Medina, Fermín Sánchez de, Martínez-Augustin, Olga
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Biological and medical sciences Cell Proliferation Female Food industries Fundamental and applied biological sciences. Psychology Immunologic Factors - pharmacology immunomodulators Interferon-gamma - secretion interleukin-10 Interleukin-10 - genetics Interleukin-10 - secretion Interleukin-1beta - secretion Interleukin-6 - secretion JNK Mitogen-Activated Protein Kinases - metabolism L-Lactate Dehydrogenase - analysis macrophages Macrophages - immunology mitogen-activated protein kinase Mitogens - pharmacology NF-kappa B - metabolism p38 Mitogen-Activated Protein Kinases - metabolism Phosphorylation Phycobiliproteins - isolation & purification Phycobiliproteins - pharmacology Phycocyanin - isolation & purification Phycocyanin - pharmacology Phycoerythrin - isolation & purification Phycoerythrin - pharmacology Plant Extracts - pharmacology Rats Rats, Wistar Rhodophycota Rhodophyta - chemistry Seaweed - chemistry secretion Spleen - cytology Spleen - immunology splenocytes T-lymphocytes T-Lymphocytes - immunology Tumor Necrosis Factor-alpha - secretion Up-Regulation
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