Full-length HLA-G1 and truncated HLA-G3 differentially increase HLA-E surface localization

Abstract Human leukocyte antigen (HLA)-E plays a role in immune tolerance induction and its transport to the cell surface is limited and dependent on the availability of HLA class I signal peptide. The role of HLA-G in regulating HLA-E surface localization remains controversial. The aim of our study...

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Veröffentlicht in:	Human immunology 2012-09, Vol.73 (9), p.898-905
Hauptverfasser:	Teklemariam, Takele, Zhao, Longmei, Hantash, Basil M
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Cell Membrane - metabolism Gene Expression Regulation Histocompatibility Antigens Class I - metabolism HLA-E Antigens HLA-G Antigens - genetics HLA-G Antigens - metabolism Humans K562 Cells Protein Transport
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