Patients on a combined antiretroviral therapy after maraviroc clinical test show no immunovirological impairment
► Maraviroc clinical test (MCT) as a method to select candidate patients to be treated with CCR5-antagonists. ► Advantages of MCT compared with other tropism assays. ► Long-term outcome of patients starting cART after MCT shows immunovirological efficacy. ► Tropism analysis during MCT shows no clini...
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Veröffentlicht in: | Antiviral research 2012-09, Vol.95 (3), p.207-211 |
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Hauptverfasser: | , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | ► Maraviroc clinical test (MCT) as a method to select candidate patients to be treated with CCR5-antagonists. ► Advantages of MCT compared with other tropism assays. ► Long-term outcome of patients starting cART after MCT shows immunovirological efficacy. ► Tropism analysis during MCT shows no clinically relevant tropism change after short-term maraviroc monotherapy.
The maraviroc clinical test (MCT) is a clinical approach to establish the indication of maraviroc treatment. In this study, we analysed the long-term outcome of patients receiving a combined antiretroviral therapy (cART) selected according to MCT results. Ninety-two consecutive HIV-infected patients underwent MCT. A virological response ( |
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ISSN: | 0166-3542 1872-9096 |
DOI: | 10.1016/j.antiviral.2012.06.007 |