Ultrabright and ultrastable near-infrared dye nanoparticles for in vitro and in vivo bioimaging

Abstract We report a new strategy of using carrier-free pure near-infrared (NIR) dye nanoparticles (NPs) to achieve highly luminescent NIR fluorescent probes for in vitro and in vivo imaging. Bis(4-(N-(2-naphthyl)phenylamino) phenyl)-fumaronitrile (NPAPF) NPs are shown to exhibit favorable biocompat...

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Veröffentlicht in:	Biomaterials 2012-11, Vol.33 (31), p.7803-7809
Hauptverfasser:	Yang, Yinlong, An, Feifei, Liu, Zhuang, Zhang, Xiujuan, Zhou, Mengjiao, Li, Wei, Hao, Xiaojun, Lee, Chun-sing, Zhang, Xiaohong
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Blood Circulation - drug effects Cell Death - drug effects Cell Line, Tumor Dentistry Fluorescence nanoparticles Fluorescent Dyes - chemical synthesis Fluorescent Dyes - chemistry Fluorescent Dyes - toxicity Fumarates - chemical synthesis Fumarates - chemistry Fumarates - toxicity Humans In vitro imaging In vivo imaging Mice Mice, Nude Microscopy, Fluorescence Nanoparticles - chemistry Nanoparticles - toxicity Nanoparticles - ultrastructure Near-infrared probes Optical Phenomena Polyethylene Glycols - chemistry Spectroscopy, Near-Infrared - methods Surface Properties - drug effects Tissue Distribution - drug effects
Online-Zugang:	Volltext
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