Administration of cyclosporin A to recipients improves the potential of mouse somatic cell nuclear-transferred oocytes to develop to fetuses

Somatic cell nuclear-transferred (SCNT) oocytes have a high potential for development in vitro, but a large proportion of embryos that are transferred to recipients is aborted before parturition. The precise mechanism for the high abortion rate is unknown, but abnormal placenta formation is frequent...

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Veröffentlicht in:	Zygote (Cambridge) 2012-08, Vol.20 (3), p.261-267
Hauptverfasser:	Tsuji, Yuta, Kato, Yoko, Tsunoda, Yukio
Format:	Artikel
Sprache:	eng
Schlagworte:	Active Transport, Cell Nucleus Animals Cloning, Organism - methods Cyclosporine - administration & dosage Embryo Transfer Embryo, Mammalian Female Fertilization in Vitro Mice Mice, Inbred C57BL Mice, Inbred DBA Mice, Inbred ICR Nuclear Transfer Techniques Oocytes - metabolism
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