Lipophilic Caffeic Acid Derivatives Protect Cells against H2O2‑Induced DNA Damage by Chelating Intracellular Labile Iron

Naturally occurring cinnamic acid derivatives are ubiquitously distributed in the plant kingdom, and it has been proposed that their consumption contributes to the maintenance of human health. However, the molecular mechanisms underlying their health keeping effects remain unknown. In the present in...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2012-08, Vol.60 (32), p.7873-7879
Hauptverfasser:	Kitsati, Natalia, Fokas, Demosthenes, Ouzouni, Maria-Dimitra, Mantzaris, Michalis D, Barbouti, Alexandra, Galaris, Dimitrios
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences caffeic acid Caffeic Acids - pharmacology Cinnamates - pharmacology cinnamic acid Coumaric Acids - pharmacology DNA damage DNA Damage - drug effects esters Food industries Fundamental and applied biological sciences. Psychology Hep G2 Cells human health Humans Hydrogen Peroxide - pharmacology iron Iron Chelating Agents - pharmacology Jurkat Cells oxidative stress Oxidative Stress - drug effects
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