Thymosin β4 is a novel potential prognostic marker in gastrointestinal stromal tumors

Thymosin beta‐4 (Tβ4) is a major actin‐sequestering molecule that contributes to cell growth, differentiation, motility, survival, mitosis and angiogenesis. It is overexpressed in certain type of carcinoma and fibrosarcoma cell lines and is associated with metastatic potential. The aim of this study...

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Veröffentlicht in:	APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2012-09, Vol.120 (9), p.689-698
Hauptverfasser:	Can, Bilge, Karagoz, Filiz, Yildiz, Levent, Yildirim, Arzu, Kefeli, Mehmet, Gonullu, Guzin, Kandemir, Bedri
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Biomarkers, Tumor - metabolism Disease-Free Survival Female Gastrointestinal Neoplasms - metabolism Gastrointestinal Neoplasms - pathology Gastrointestinal stromal tumor Gastrointestinal Stromal Tumors - metabolism Gastrointestinal Stromal Tumors - pathology Host-tumor relations. Immunology. Biological markers Humans Immunohistochemistry Kaplan-Meier Estimate Male Medical sciences Middle Aged Retrospective Studies Thymosin - metabolism thymosin beta-4 Tumors vascular endothelial growth factor Vascular Endothelial Growth Factor A - metabolism
Online-Zugang:	Volltext
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