Dynamics of diffusivity and pressure drop in flow-through and parallel-flow bioreactors during tissue regeneration

In this study, transport characteristics in flow‐through and parallel‐flow bioreactors used in tissue engineering were simulated using computational fluid dynamics. To study nutrient distribution and consumption by smooth muscle cells colonizing the 100 mm diameter and 2‐mm thick scaffold, effective...

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Veröffentlicht in:	Biotechnology progress 2012-07, Vol.28 (4), p.1045-1054
Hauptverfasser:	Podichetty, Jagdeep T., Dhane, Dhananjay V., Madihally, Sundararajan V.
Format:	Artikel
Sprache:	eng
Schlagworte:	3D scaffold Animals Biological and medical sciences bioreactor design Bioreactors Biotechnology Cell Count Cell Proliferation chitosan Chitosan - chemistry Computer Simulation diffusivity Fundamental and applied biological sciences. Psychology gelatin Gelatin - chemistry Glucose - metabolism Hydrodynamics Kinetics Methods. Procedures. Technologies Myocytes, Smooth Muscle - cytology Myocytes, Smooth Muscle - metabolism Permeability Porosity Pressure Rats Tissue Engineering - instrumentation Tissue Engineering - methods Tissue Scaffolds - chemistry Various methods and equipments
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